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Multilocus genotyping reveals a polyphyletic pattern among naturally antimony-resistant Leishmania braziliensis isolates from Peru
(Elsevier, 2011)
In order to understand the epidemiological dynamics of antimonial (Sb V) resistance in zoonotic tegumentary leishmaniasis and its link with treatment outcome, we analyzed the population structure of 24 Peruvian Leishmania ...
Application of crispr/cas9-based reverse genetics in leishmania braziliensis: Conserved roles for hsp100 and hsp23
(MDPI, 2020)
The protozoan parasite Leishmania (Viannia) braziliensis (L. braziliensis) is the main cause of human tegumentary leishmaniasis in the New World, a disease affecting the skin and/or mucosal tissues. Despite its importance, ...
Variations in macrophage migration inhibitory factor gene are not associated with visceral leishmaniasis in India
(Elsevier Ltd, 2019-05)
The host genetic factors play important role in determining the outcome of visceral leishmaniasis (VL). Macrophage migration inhibitory factor (MIF) is an important host cytokine, which is a key regulator of innate immune ...
Análisis comparativo de las respuestas transcripcionales de cinco especies de Leishmania frente al antimonio trivalente.
Leishmaniasis is considered a neglected tropical disease for which there is no vaccine. On the other hand, first-line drugs have shown an increase in therapeutic failures, among other causes due to the acquisition of ...
KDNA genetic signatures obtained by LSSP-PCR analysis of Leishmania (Leishmania) infantum isolated from the new and the old world
(Public Library Of Science, 2014)
Estudo da variabilidade genética intraespecífica de Leishmania (Leishmania) infantum em amostras de cães e humanos
(Universidade Federal de Minas GeraisUFMG, 2013-02-22)
Visceral leishmaniasis (VL) is a disease distributed worldwide and potentially fatal to humans if not diagnosed and early treated. In addition to human, other mammals are also affected, especially dogs in the urban context, ...