Now showing items 1-10 of 361
The antifungal compound butenafine eliminates promastigote and amastigote forms of Leishmania (Leishmania) amazonensis and Leishmania (Viannia) braziliensis
The production of ergosterol lipid, important for the Leishmania membrane homeostasis, involves different enzymes. This pathway can be blocked to azoles and allylamines drugs, such as Butenafine. The aim of the present ...
Identification of a major 72 kilodalton surface antigen in twelve isolates of Leishmania braziliensis braziliensis
(Molecular and Biochemical Parsitology, 1987)
The study of the surface antigens of Leishmania braziliensis braziliensis revealed a great homogeneity among ten strains isolated from Bolivia and two reference strains from Brazil and Belize. A 72 kDa major protein, ...
Antigenic specificity of the 72-kilodalton major surface glycoprotein of Leishmania braziliensis braziliensis
(Journal of Clinical Microbiology, 1991)
We examined the expression and the antigenicity of the major surface polypeptides of Leishmania braziliensis braziliensis and Leishmania donovani chagasi, parasites which commonly coexist in the same endemic areas of ...
Identification of cytoplasmic soluble antigens related to the major surface antigens of Leishmania braziliensis braziliensis and L. donovani chagasi
(Parasitol Res., 1990)
Abstract. This study describes the identification of aqueous-soluble antigens in Leishmania promastigotes immunologically and biochemically closely related to the major surface antigen. Proteins from surface-iodinated L. ...
Characterization of anti-silencing factor 1 in Leishmania major
(FUNDACO OSWALDO CRUZRIO DE JANEIRO, 2012)
Anti-silencing factor 1 (ASF1) is a histone chaperone that contributes to the histone deposition during nucleosome assembly in newly replicated DNA. It is involved in chromatin disassembly, transcription activation and in ...
Analysis and chromosomal mapping of Leishmania (Leishmania) amazonensis amastigote expressed sequence tags
(Instituto Oswaldo Cruz, Ministério da Saúde, 2007-09-01)
The characterization of expressed sequence tags (ESTs) generated from a cDNA library of Leishmania (Leishmania) amazonensis amastigotes is described. The sequencing of 93 clones generated new L. (L.) amazonensis ESTs from ...
Virulent or avirulent (dhfr-ts??) Leishmania major elicit predominantly a type-1 cytokine response by human cells in vitro
(Clinical and Experimental Immunology, 2000)