Buscar
Mostrando ítems 1-10 de 168
Raloxifene decreases cell viability and migratory potential in prostate cancer cells (LNCaP) with GPR30/GPER1 involvement
(2019-07-01)
Objectives: This study evaluated raloxifene (ral) effects on LNCaP prostate tumour cells modulating the activity of GPER1/GPR30 receptors. Methods: LNCaP cells were submitted for 40/120 min and 12 h to the following ...
Decreased c-Abl activity in PC-3 and LNCaP prostate cancer cells overexpressing the early growth response-1 protein
(Spandidos Publ, 2014)
Early growth response-1 (Egr-1) and the non-receptor protein tyrosine kinase (c-Abl) are 2 response genes that can act as regulators of cell growth and apoptosis in response to stress. Both Egr-1 and c-Abl regulate cell ...
Development of pipette tip gap closure migration assay (s-ARU method) for studying semi-adherent cell lines
(2018-01-01)
This work presents a pipette tip gap closure migration assay prototype tool (semi-adherent relative upsurge—s-ARU—method) to study cell migration or wound healing in semi-adherent cell lines, such as lymph node carcinoma ...
Regulation of cell survival by resveratrol involves inhibition of NFκB-regulated gene expression in prostate cancer cells
(2009)
BACKGROUND. Polyphenols have been proposed as antitumoral agents. We have shown that resveratrol (RES) induced cell cycle arrest and promoted apoptosis in prostate cancer cells by inhibition of the PI3K pathway. The RES ...
Association of increased levels of TGF-β1 and p14ARF in prostate carcinoma cell lines overexpressing Egr-1
(Spandidos Publications, 2014)
The present study examined the effect of the overexpression of early growth response gene (Egr-1) on transforming growth factor β-1 (TGF-β1) and p14ARFlevels, in PC-3 and LNCaP prostate carcinoma cell lines. Amplification ...
Fibronectin induces MMP2 expression in human prostate cancer cells
(2013-01-25)
High-grade prostate cancers express high levels of matrix metalloproteinases (MMPs), major enzymes involved in tumor invasion and metastasis. However, the tumor cell lines commonly employed for prostate cancer research ...
Fibronectin induces MMP2 expression in human prostate cancer cells
(2013-01-25)
High-grade prostate cancers express high levels of matrix metalloproteinases (MMPs), major enzymes involved in tumor invasion and metastasis. However, the tumor cell lines commonly employed for prostate cancer research ...
Emprego do peptídeo 99mTc-HYNIC-ßAla-Bombesina(7-14) na identificação de tumor de próstata da linhagem LNCaP em modelo experimental
(Universidade Federal de Minas GeraisUFMG, 2012-02-27)
Prostate cancer is one of the most prevalent tumors in men, showing high mortality rates. Current diagnostic methods are not able to identify early prostate carcinoma, often resulting in a late diagnosis with established ...
Role of 20-Hydroxyeicosatetraenoic Acid (20-HETE) in androgen-mediated cell viability in prostate cancer cells
(Springer, 2017-08)
20-Hydroxyeicosatetraenoic acid (20-HETE) is generated intracellularly through the ω-hydroxylation of arachidonic acid by the cytochrome P450 (in humans, CYP4A11 and CYP4F2). 20-HETE induces mitogenic responses in different ...