Fatty acids (FAs) are important compounds either used for energy production through β-oxidation, for membrane lipid synthesis, or for production of lipid mediators (oxylipins) through oxidations. FAs are also cytotoxic and ...

Melittin (ML) is a small peptide of 26 residues rich in arginine (Arg) and lysine (Lys). Several studies have been done to understand the mechanism of interaction with neutral and negatively charged lipids. However, it is ...

The interactions of proteins with membrane surfaces are important to many biological processes, including signaling, recognition, and membrane trafficking, cell division and cell structure. When the Fluid Mosaic Model (FMM) ...

We demonstrated previously that acetylated tubulin inhibits plasma membrane Ca 2 +-ATPase (PMCA) activity in plasma membrane vesicles (PMVs) of rat brain through a reversible interaction. Dissociation of the PMCA/tubulin ...

Neurotransmitter receptors, the macromolecules specialized in decoding the chemical signals encrypted in the chemical signaling mechanism in the nervous system, occur either at the somatic cell surface of chemically excitable ...

The lipid composition of biological membranes is key for cell viability. Nevertheless, and despite their central role in cell function, our understanding of membrane physiology continues to lag behind most other aspects ...

Background: When purified phagosomes are incubated in the presence of actin under appropriate conditions, microfilaments start growing from the membrane in a process that is affected by ATP and the lipid composition of the ...

UPAR is a GPI anchored protein, which is found in both lipid rafts and in more fluid regions of the plasma membrane. We have studied the role of the ligand uPA on uPAR localization and on the composition of the lipid ...