Macrophage activation is intimately linked to metabolic reprogramming. Inflammatory (M1) macrophages are able to sustain inflammatory responses and to kill pathogens, mostly by relying on aerobic glycolysis and fatty acid ...

Objective To investigate the effect of different dietary oils on the main hepatic enzymes involved in metabolism and their impact on oxidative stress status. Methods Twenty-four male Wistar rats were fed for 60 d on the ...

Prenatal hyperandrogenism is hypothesized as one of the main factors contributing to26 the development of polycystic ovary syndrome (PCOS). PCOS patients have high risk27 of developing fatty liver and steatosis. This study ...

Recent lines of evidences indicate that several pathological conditions, as cardiovascular diseases, are associated with oxidative stress. In order to validate a butylated hydroxytoluene (BHT)-induced experimental model ...

Skeletal muscle is one of the main regulators of carbohydrate and lipid metabolism in our organism, and therefore, it is highly susceptible to changes in glucose and fatty acid (FA) availability. Skeletal muscle is an ...

OBJECTIVE: Peroxisome proliferator activated receptors (PPARs), known regulators of lipid homeostasis in different tissues, are crucial during placental development. In this work we aim to determine whether PPARs activation ...

Dusky grouper is an important commercial fish species in many countries, but some factors such as overfishing has significantly reduced their natural stocks. Aquaculture emerges as a unique way to conserve this species, ...