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Evaluation of Reduced Graphene Oxide Modified with Antimony and Copper Nanoparticles for Levofloxacin Oxidation
(2018-09-01)
This work presents, for the first time, the oxidation mechanism of levofloxacin combining electrochemical experiments and molecular modelling techniques. Levofloxacin is one of the most widely used antibiotics in the world. ...
Increased Doses Lead to Higher Drug Exposures of Levofloxacin for Treatment of Tuberculosis
(American Society for Microbiology, 2018)
Patients with multidrug-resistant tuberculosis in Peru and South Africa were randomized to a weight-banded nominal dose of 11, 14, 17, or 20 mg/kg/day levofloxacin (minimum, 750 mg) in combination with other second-line ...
Evaluation of the critical points in the validation of 500 mg levofloxacin tablets for dissolution profile
(2016)
The method was validated by ultraviolet spectrophotometry for the
determination of levofloxacin 500 mg tablets using dissolution profiles
to establish therapeutic equivalence. The parameters were satisfactory
according ...
New operational mode of an electrochemical reactor and its application to the degradation of levofloxacin
(2017-10-01)
The flow-by electrochemical reactor is generally used in batch mode with extended process time in order to achieve high efficiency in the removal of organic contaminant from aqueous solution. Moreover, the batch mode system ...
Grinding effect on levofloxacin hemihydrate
(Springer, 2015-02-01)
The grinding techniques were used in different pharmacotechnical process. the control of the effect of grinding in solid state properties of drugs is very important, mainly in hydrated drugs. Levofloxacin hemihydrate (LVF) ...
Pharmacokinetics of levofloxacin after single intravenous and oral administration, and its interaction with sucralfate in mixed-breed dogs
(Taylor & Francis Ltd, 2020-07)
The study aims to establish the plasma pharmacokinetic parameters of levofloxacin in mixed-breed dogs, at a single dose of 5 mg/kg, intravenously, orally only and orally with sucralfate pre-treatment (1 g per animal), to ...
Development of antimicrobial hybrid mesoporous silver phosphate-pectin microspheres for control release of levofloxacin
(Elsevier Science, 2015-12-30)
Pectin was used as nucleation agent in the synthesis of spherical mesoporous Ag3PO4 microspheres for the development of dual antimicrobial carrier containing a fluoroquinolone. The hybrid Ag3PO4-pectin microspheres were ...
Characterization of smart auto-degradative hydrogel matrix containing alginate lyase to enhance levofloxacin delivery against bacterial biofilms
(Elsevier Science, 2015-12)
The aim of the present work is the characterization of smart auto-degradable microspheres composed of calcium alginate/high methoxylated pectin containing an alginate lyase (AL) from Sphingobacterium multivorum and ...