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Imaging nanometer-sized α-synuclein aggregates by superresolution fluorescence localization microscopy
(Cell Press, 2012-04)
The morphological features of alpha-synuclein (AS) amyloid aggregation in vitro and in cells were elucidated at the nanoscale by far-field subdiffraction fluorescence localization microscopy. Labeling AS with rhodamine ...
Messages diffuse faster than messengers
(National Academy of Sciences, 2006-12)
In many cell-signaling pathways, information is transmitted by the diffusion of messenger molecules. Diffusion coefficients characterize the messenger's spatial range and the characteristic times of signal propagation. ...
Development of a non-radioactive molecular hybridization probe for detecting Strawberry mottle virus in strawberry
(2016)
The vegetative propagation of strawberries favors transmission of systemic pathogens, such as viruses, which are one of the main yield-limiting factors for this crop. More than 20 viruses have been described as infecting ...
Membrane binding, internalization, and sorting of alpha-synuclein in the cell
(NLM (Medline), 2018-08)
Alpha-synuclein (aSyn) plays a crucial role in Parkinson's disease (PD) and other synucleinopathies, since it misfolds and accumulates in typical proteinaceous inclusions. While the function of aSyn is thought to be related ...