Targeting Mycobacterium tuberculosis peptidoglycans with beta-lactam antibiotics represents a strategy to address increasing resistance to antitubercular drugs. beta-Lactams inhibit peptidoglycan synthases such as ...

Backgrounds/Aims: Canalicular membrane enzymes are normally released into bile by partially known processes. This study was undertaken to investigate whether hepatocellular cholestasis induced in rats by ethynylestradiol ...

Helicobacter pylori (H. pylori) is the major risk factor associated with the development of gastric cancer. Multiple virulence factors contribute to its pathogenesis, and recently, the secreted gamma­glutamyl transpeptidase ...

Hepatic ischemia-reperfusion (I-R) injury frequently is associated with cholestasis. However, the underlying mechanisms are not fully understood. The aim of the study is to assess bile secretory function in vivo in rats ...