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Production, physicochemical characterization, and anticancer activity of methotrexate-loaded phytic acid-chitosan nanoparticles on HT-29 human colon adenocarcinoma cells
(Elsevier, 2020-09-01)
Methotrexate-loaded phytic acid-chitosan nanoparticles were synthesized by ionic gelation assisted by high-intensity sonication. The nanoparticles were characterized by particle size, polydispersity index, zeta potential ...
Preparation, physicochemical and biopharmaceutical characterization of oxcarbazepine-loaded nanostructured lipid carriers as potential antiepileptic devices
(Editions Sante, 2021-06)
Epilepsy is the second most common chronic central nervous system disorder. Oxcarbazepine (OXC) is an antiepileptic drug with low solubility in aqueous media but is used for the treatment of both focal and generalized ...
Niosomes encapsulated in biohydrogels for tunable delivery of phytoalexin resveratrol
(Royal Society of Chemistry, 2019-02)
A series of biohydrogels based on mixtures of kappa-carrageenan (κ-carrageenan, κ-C) and gelatin were evaluated as potential soft delivery vehicles for the encapsulation and subsequent release of non-ionic surfactant ...
Formulation of a modified release metformin.HCl matrix tablets : influence of some hydrophilic polymers on the release rate and in-vitro evaluation
(Universidade de São Paulo, Faculdade de Ciências FarmacêuticasDiseño y Formulación de Medicamentos Cosméticos y AfinesSao Paulo, Brasil, 2022)
Ciprofloxacin-intercalated layered double hydroxide-in-hybrid films as composite dressings for controlled antimicrobial topical delivery
(Elsevier Science, 2020-06)
Films based on biopolymers and loaded with antimicrobial agents are convenient pharmaceutical dosage forms for topical application. Inorganic carriers loaded with these agents lead to composite materials, which combined ...
Lipid nanoparticles-Metvan: Revealing a novel way to deliver a vanadium compound to bone cancer cells
(Royal Society of Chemistry, 2019-07)
Cancer is one of the main causes of mortality worldwide. Common therapy schemes are always based on chemotherapy, radiotherapy and/or surgery. Among chemotherapeutics, vanadium compounds have recently emerged as non-platinum ...
Nanoparticulated Systems Based on Natural Polymers Loaded with Miconazole Nitrate and Lidocaine for the Treatment of Topical Candidiasis
(Springer, 2020-10-08)
People with weakened immune systems are at risk of developing candidiasis which is a fungal infection caused by several species of Candida genus. In this work, polymeric nanoparticles containing miconazole nitrate and the ...
Films based on soy protein-agar blends for wound dressing: Effect of different biopolymer proportions on the drug release rate and the physical and antibacterial properties of the films
(SAGE Publications, 2018-04)
No single material can provide all requirements for wound dressings. Here, we evaluated the influence of different soy protein isolate and agar proportions (3:1, 1:1, and 1:3) in blend films on some of their physical-chemical ...