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Meridianins, a new family of protein kinase inhibitors isolated from the Ascidian Aplidium meridianum

Gompel, Marie; Leost, Maryse; Bal, Elisa Dora; Puricelli, Lydia Ines; Hernandez Franco, Laura; Palermo, Jorge Alejandro; Meijer, Laurent (Pergamon-Elsevier Science Ltd, 2004-04)

Meridianins are brominated 3-(2-aminopyrimidine)-indoles which are purified from Aplidium meridianum, an Ascidian from the South Atlantic (South Georgia Islands). We here show that meridianins inhibit various protein kinases ...

The Cross-talk Between Angiotensin And Insulin Differentially Affects Phosphatidylinositol 3-kinase- And Mitogen-activated Protein Kinase-mediated Signaling In Rat Heart: Implications For Insulin Resistance.

Carvalheira, José B C; Calegari, Vivian C; Zecchin, Henrique G; Nadruz, Wilson; Guimarães, Regina B; Ribeiro, Eliane B; Franchini, Kleber G; Velloso, Lício A; Saad, Mario J A (2003)

Protein kinase CK2: An ugly duckling in the kinome pond

Pinna, L. A.; Allende, J. E. (2009)

Early Activation Of The Multicomponent Signaling Complex Associated With Focal Adhesion Kinase Induced By Pressure Overload In The Rat Heart.

Franchini, K G; Torsoni, A S; Soares, P H; Saad, M J (2000)

The casein kinase 1α gene of Drosophila melanogaster is developmentally regulated and the kinase activity of the protein induced by DNA damage

Santos, João A.; Logarinho, Elsa; Tapia, Claudio; Allende, Catherine C.; Allende, Jorge E.; Sunkel, Claudio E. (1996)

We report the molecular cloning and characterisation of the first CK1 (casein kinase) gene of Drosophila melanogaster (dmCK1). The protein sequence (DMCK1) shares significant homology with other mammalian CK1 protein kinases ...

Cross-talk Between The Insulin And Angiotensin Signaling Systems.

Velloso, L A; Folli, F; Sun, X J; White, M F; Saad, M J; Kahn, C R (1996)

Allosteric Regulation of Protein Kinases Downstream of PI3-Kinase Signalling

Leroux, Alejandro Ezequiel; Gross, Lissy Zoe Florens; Sacerdoti, Mariana; Biondi, Ricardo Miguel (Springer, 2019)

Allostery is a basic principle that enables proteins to process and transmit cellular information. Protein kinases evolved allosteric mechanisms to transduce cellular signals to downstream signalling components or effector ...

Endogenous Protein Phosphorylation And Casein Kinase Activity During Seed Development In Araucaria Angustifolia.

Machado, Edna Lôbo; Chiesse da Silva, Alba; da Silva, Márcio J; Leite, Adilson; Ottoboni, Laura M M (2002)

Protein tyrosine kinases in Schistosoma mansoni

Bahia, Diana; Andrade, Luiza Freire; Ludolf, Fernanda; Mortara, Renato Arruda; Oliveira, Guilherme Corrêa de (2013)

Glycogen synthase kinase (GSK)-3 and the double-strand RNA-dependent kinase, PKR: When two kinases for the common good turn bad

Piazzi, Manuela; Bavelloni, Alberto; Faenza, Irene; Blalock, William

Glycogen synthase kinase (GSK)-3α/β and the double-stranded RNA-dependent kinase PKR are two sentinel kinases that carry-out multiple similar yet distinct functions in both the cytosol and the nucleus. While these kinases ...

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