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KIR2DL4 genetic diversity in a Brazilian population sample: implications for transcription regulation and protein diversity in samples with different ancestry backgrounds
(2021-06-01)
KIR2DL4 is an important immune modulator expressed in natural killer cells; HLA-G is its main ligand. We have characterized the KIR2DL4 genetic diversity by considering the promoter, all exons, and all introns in a highly ...
KIR genes polymorphism in Argentinean Caucasoid and Amerindian populations
(Wiley Blackwell Publishing, Inc, 2007-12)
In natural killer cells, killer immunoglobulin-like receptors (KIRs) loci code for either inhibitory or activating receptors, and according to the number of genes present in each individual, it is possible to identify a ...
Variabilidade genética e estrutura haplotípica do gene kir2dl4 avaliada em uma amostra brasileira
(Universidade Estadual Paulista (Unesp), 2019-03-11)
O gene KIR2DL4 codifica um importante receptor de células Natural Killer (NK). O único ligante de KIR2DL4 conhecido é a molécula HLA-G, expressa principalmente na placenta, modulando a ação das células NK durante a gestação. ...
Diversity of the KIR gene cluster in an urban Brazilian population
(SPRINGERNEW YORK, 2012)
The activity of natural killer cells depends on the balance between activating and inhibitory signals coming from their receptors. Among these are the killer cell immunoglobulin-like receptors (KIR) that recognize specific ...
Influência de polimorfismos de genes KIR e de seus ligantes HLA na susceptibilidade ao dengueInfluence of KIR gene polymorphisms and their HLA ligands on susceptibility to dengue
(Universidade Estadual de MaringáBrasilDepartamento de Análises Clínicas e BiomedicinaPrograma de Pós-Graduação em Biociências e FisiopatologiaUEMMaringá, PRCentro de Ciências da Saúde, 2018)