Now showing items 1-10 of 18
SOLVENT-FREE MICROWAVE MICHAEL ADDITION OF ISATIN AND ANILINE SCHIFF BASE OF ISATIN TO α,β-UNSATURATED ESTERS
(Sociedad Chilena de Química, 2011)
Mutagenicity and genotoxicity of isatin in mammalian cells in vivo
(Elsevier B.V., 2011-02-03)
Isatin (1H-indole-2,3-dione) is a synthetically versatile substrate used for the synthesis of heterocyclic compounds and as a raw material for drug synthesis. Isatin and its derivatives demonstrate anticonvulsant, ...
Isatin-Schiff base copper(II) complexes-A DFT study of the metal-ligand bonding situation
Herein, we report results of calculations based on density functional theory (BP86/TZVP) of a set of isatin-Schiff base copper(II) and related complexes, 1-12, that have shown significant pro-apoptotic activity toward ...
In vitro assessment of the cytotoxic, apoptotic, and mutagenic potentials of Isatin
Isatin (1H-indole-2,3-dione) is a chemical found in various medicinal plant species and responsible for a broad spectrum of pharmacological and biological properties that may be beneficial to human health, as an anticonvulsant, ...
Inhibition of tumor necrosis factor-alpha and cyclooxigenase-2 by Isatin: A molecular mechanism of protection against TNBS-induced colitis in rats
(Elsevier Ireland LtdClareIrlanda, 2014)
COBALT(II), Ni(II), Cu(II), Zn(II), CD(II), Hg(II), U0(2)(VI) AND th(IV) COMPLEXES FROM ONNN SCHIFF BASE LIGAND
(Sociedad Chilena de Química, 2008)
Crystal structure, Hirshfeld analysis and molecular docking with the vascular endothelial growth factor receptor-2 of (3Z)-5-fluoro-3-(hydroxyimino)indolin-2-one Martins Bianca Barreto
The reaction between 5-fluoroisatin and hydroxylamine hydrochloride in acidic ethanol yields the title compound, C8H5FN2O2, whose molecular structure matches the asymmetric unit and is nearly planar with an r.m.s. deviation ...
Crystal structure of (3E)-5-nitro-3-(2-phenylhydrazinylidene)-1H-indol-2(3H)-one
The reaction between 5-nitroisatin and phenylhydrazine in acidic ethanol yields the title compound, C14H10N4O3, whose molecular structure deviates slightly from a planar geometry (r.m.s. deviation = 0.065Å for the mean ...
Aqueous Morita-Baylis-Hillman Reaction of Unprotected Isatins with Cyclic Enones
(Amer Chemical SocWashingtonEUA, 2013)