Now showing items 1-10 of 977
Fatty acid regulation of voltage- and ligand-gated ion channel function
(Frontiers Research Foundation, 2016-11-28)
Free fatty acids (FFA) are essential components of the cell, where they play a key role in lipid and carbohydrate metabolism, and most particularly in cell membranes, where they are central actors in shaping the physicochemical ...
Probing the pore size of the hemocyanin channel
We have studied single-channel conductance for different monovalent cations and streaming potentials caused by osmotic gradients of non-electrolytes in hemocyanin-treated membranes. We have found that the smaller ion, which ...
Structure and function of channels and channelogs as studied by computational chemistry
Acid-sensing ion channels and transient-receptor potential ion channels in zebrafish taste buds
Sensory information from the environment is required for life and survival, and it is detected by specialized cells which togethermakeup the sensory system. The fish sensory system includes specialized organs that are ...
A chloride channel from human placenta reconstituted into giant liposomes
(Mosby-Year book, 1995)
OBJECTIVE: Ion channels play important roles in epithelial transport, but they are difficult to access for conventional electrophysiologic studies in intact placenta. The purpose of this work was to explore the suitability ...
Oxidative stress-modulated TRPM ion channels in cell dysfunction and pathological conditions in humans
The transient receptor potential melastatin (TRPM) protein family is an extensive group of ion channels expressed in several types of mammalian cells. Many studies have shown that these channels are crucial for performing ...
Ion channels from the Bacillus subtilis plasma membrane incorporated into planar lipid bilayers
Fusion of Bacillus subtilis plasma membrane vesicles with planar lipid bilayers induced the appearance of discrete current fluctuations characteristic of ion channels. These channels showed a wide range of conductances and ...
Counting channels: a tutorial guide on ion channel fluctuation analysis
(American Physiological Society, 2002)
Ion channels open and close in a stochastic fashion, following the laws of probability. However, distinct from tossing a coin or a die, the probability of finding the channel closed or open is not a fixed number but can ...
Ion channels from chemosensory olfactory neurons
(Kluwer Academic Publishers-Plenum Publishers, 1988)
The olfactory epithelium has the ability to respond to a large number of volatile compounds of small molecular weight. Ultimately, such a property lies on a specialized type of neuron, the olfactory receptor cell. In the ...
Blocking of human T lymphocyte activation by channel antagonists
It has been established that early events in lymphocyte activation involve a rise in intracellular Ca++ as well as changes in the flux of other ions. Although a Ca++ channel has been postulated to participate in the early ...