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Estradiol decreases iodide uptake by rat thyroid follicular FRTL-5 cells
(Associação Brasileira de Divulgação Científica, 2001-02-01)
Estradiol has well-known indirect effects on the thyroid. A direct effect of estradiol on thyroid follicular cells, increasing cell growth and reducing the expression of the sodium-iodide symporter gene, has been recently ...
Excess Iodide Induces an Acute Inhibition of the Sodium/Iodide Symporter in Thyroid Male Rat Cells by Increasing Reactive Oxygen Species
(2015)
Na+/I- symporter (NIS) mediates iodide (I-) uptake in the thyroid gland, the first and rate-limiting step in the biosynthesis of the thyroid hormones. The expression and function of NIS in thyroid cells is mainly regulated ...
Excess Iodide Induces an Acute Inhibition of the Sodium/Iodide Symporter in Thyroid Male Rat Cells by Increasing Reactive Oxygen Species
(2015)
Na+/I- symporter (NIS) mediates iodide (I-) uptake in the thyroid gland, the first and rate-limiting step in the biosynthesis of the thyroid hormones. The expression and function of NIS in thyroid cells is mainly regulated ...
Characterization of small-molecule inhibitors of the sodium iodide symporter
The sodium/iodide symporter (NIS) mediates the active transport of iodide from the bloodstream into thyrocytes. NIS function is strategic for the diagnosis and treatment of various thyroid diseases. In addition, a promising ...
Na+/ I- symporter (NIS) expression and localization during rapid transport inhibition by iodide excess.
(2010)
Preferred Presentation Method: Poster Presentation
Abstract: Iodide (I-) uptake is the first and limiting step of thyroid hormone synthesis and is mediated by Na+/I- symporter
(NIS). The expression and function of NISis ...
Novel sodium/Iodide symporter compound heterozygous pathogenic variants causing dyshormonogenic congenital hypothyroidism
(Mary Ann Liebert, 2019-07)
Iodide transport defect (ITD) is an autosomal recessive disorder caused by deficient iodide accumulation into the thyroid follicular cell. ITD is an uncommon cause of dyshormonogenetic congenital hypothyroidism that results ...
Excess iodide induces an acute inhibition of the sodium/iodide symporter in thyroid male rat cells by increasing reactive oxygen species
(Endocrine Society, 2015)
Na+/I- symporter (NIS) mediates iodide (I-) uptake in the thyroid gland, the first and rate-limiting step in the biosynthesis of the thyroid hormones. The expression and function of NIS in thyroid cells is mainly regulated ...
Amphotericin B mediates killing in Cryptococcus neoformans through the induction of a strong oxidative burst
(Elsevier B.V., 2011-05-01)
We studied the effects of Amphotericin B (AmB) on Cryptococcus neoformans using different viability methods (CFUs enumeration, XTT assay and propidium iodide permeability). After 1 h of incubation, there were no viable ...
Amphotericin B mediates killing in Cryptococcus neoformans through the induction of a strong oxidative burst
(Elsevier B.V., 2011-05-01)
We studied the effects of Amphotericin B (AmB) on Cryptococcus neoformans using different viability methods (CFUs enumeration, XTT assay and propidium iodide permeability). After 1 h of incubation, there were no viable ...