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Effect of a biological response modifier on cellular death mechanisms at drying off
(Cambridge University Press, 2008-05)
Agents that increase natural protective mechanisms have been proposed for prevention and treatment of intramammary infections. The objective of this study was to describe the effects of a single intramammary infusion of a ...
Effects of chronic Staphylococcus aureus infection on immunological parameters and functionality of macrophages isolated from bovine mammary secretions
(Academic Press Ltd - Elsevier Science Ltd, 2019-09)
The aim of this study was to characterize the effects of chronic S. aureus intramammary infection (IMI) on local innate and adaptive immune response during active involution. Cows in late lactation that were either uninfected ...
Involvement of matrix metalloproteinases and their inhibitors in Staphylococcus aureus chronically infected bovine mammary glands during active involution
(Elsevier, 2021-04)
The aim of this study was to characterize the protein expression of matrix metalloproteinase-2 (MMP-2) and ‐− 9 and their inhibitors (TIMP-1 and -2) in mammary tissue of dairy cows with naturally occurring chronic S. aureus ...
Characterization of immune response in Staphylococcus aureus chronically infected bovine mammary glands during active involution
(2017-10)
The aim of this study was to characterize the immune response in Staphylococcus aureus chronically infected bovine mammary glands during active involution. Twenty-one Holstein non-pregnant cows in late lactation either ...
The effect of a single intramammary infusion of a biological response modifier in cows at drying off
(Springer, 2010-08)
Biological response modifiers (BRM) are compounds that interact with the immune system to regulate specific aspects of host response. The objective of this study was to describe clinical and morphological changes during ...
Proliferation-apoptosis balance in Staphylococcus aureus chronically infected bovine mammary glands during involution
(2017-05)
The objective of this study was to determine whether Staphylococcus aureus chronic intramammary infection (IMI) influences expression of proteins related to regulation of proliferation and apoptosis processes and ...
Staphylococcus aureus chronic intramammary infection modifies protein expression of transforming growth factor beta (TGF-β) subfamily components during active involution
(2014-02)
The objectives of this study were to determine whether Staphylococcus aureus chronic intramammary infection (IMI) influences protein expression of TGF-β subfamily components and collagen I and to examine the histomorphometric ...
Morphological changes and oxidative stress in rat prostate exposed to a non-carcinogenic dose of cadmium
(Elsevier Ireland, 2004-11)
Cadmium chloride is an environmental toxicant implicated in human prostate carcinogenesis. The mechanism of its toxicity is far from fully understood. This study evaluates the effect of exposure to an oral non-carcinogenic ...
STAT5 transcriptional activity is impaired by LIF in a mammary epithelial cell line
(Academic Press Inc Elsevier Science, 2007-05)
Gene regulation mediated by STAT factors has been implicated in cellular functions with relevance to a variety of processes. Particularly, STAT5 and STAT3 play a crucial role in mammary epithelium displaying reciprocal ...
Expression of the mRNA stability regulator Tristetraprolin is required for lactation maintenance in the mouse mammary gland
(Impact Journals, 2017-11)
Tristetraprolin (TTP), an mRNA-binding protein that negatively controls levels of inflammatory factors, is highly expressed in the lactating mouse mammary gland. To determine the biological relevance of this expression ...