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Pharmacokinetics of Melphalan after Intravitreal Injection in a Rabbit Model
(Mary Ann Liebert, 2016-05)
Purpose: Although widely used for vitreous seed control in retinoblastoma patients, currently there are no data on melphalan pharmacokinetics after intravitreal injections. Therefore, in this study, we characterized the ...
Assessment of retinoblastoma RNA reflux after intravitreal injection of melphalan
(B M J Publishing Group, 2018-03)
Background: Intravitreal injection of chemotherapy in retinoblastoma eyes with vitreous seeds may lead to a risk of extraocular tumour dissemination that has not been assessed so far.
Aims: To develop a sensitive and ...
Comparative Study of Analgesic Effectiveness Using Three Different Anesthetic Techniques for Intravitreal Injection of Bevacizumab
(SLACK INC, 2009)
BACKGROUND AND OBJECTIVE: To compare the analgesic effectiveness and aesthetic appearance associated with topical, subconjunctival, and peribulbar anesthesia for intravitreal bevacizumab injection. PATIENTS AND METHODS: ...
Face mask contamination during Covid-19 pandemia. A study on patients receiving intravitreal injections
PURPOSE: To investigate the bacterial growth in the surgical face masks used by patients who received intravitreal injections and study the effect of povidone-iodine on the periocular area (PA) of masks. METHODS: Forty ...
Optimizing the storage of chemotherapeutics for ophthalmic oncology: Stability of topotecan solution for intravitreal injection
(Taylor & Francis, 2020-07)
Background: Intravitreal administration of topotecan shows activity against tumor vitreous seeding in the conservative treatment of retinoblastoma, a malignant tumor originated in the retina of small children. Adequate ...
Ocular toxicity of intravitreous adalimumab (Humira) in the rabbit
(SPRINGER, 2008)
Purpose To evaluate the ocular toxicity of escalating doses of intravitreous adalimumab (Humira) in the rabbit eye. Methods Twelve New Zealand albino rabbits received unilateral intravitreous injections of 0.1 ml of ...
Randomized Controlled Trial Comparing the Effects on Eye Pressure of Intravitreal Triamcinolone Injection versus Intravitreal Dexamethasone (Ozurdex) Implant in Patients with Diabetic Macular Edema TRIDEX TRIAL
(Assoc Research Vision Ophthalmology Inc, 2020-06-01)
Ex vivo evaluation of intravitreal mesenchymal stromal cell viability using bioluminescence imaging
(BioMed Central, 2018)
Abstract
Background
Bone marrow-derived mesenchymal stromal cell (MSC) therapy is a promising treatment for several degenerative ocular diseases; however, no reproducible ...
Ocular and systemic toxicity of intravitreal topotecan in rabbits for potential treatment of retinoblastoma
(Elsevier, 2013-03)
Treatment of intraocular retinoblastoma with vitreous seeding is a challenge. Different routes of chemotherapy administration have been explored in order to attaining pharmacological concentrations into the posterior ...