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A Novel Calcium-Activated Potassium Channel Controls Membrane Potential and Intracellular pH in Trypanosoma cruzi
(Frontiers Media S.A., 2020-01)
Trypanosoma cruzi develops in environments where nutrient availability, osmolarity, ionic concentrations, and pH undergo significant changes. The ability to adapt and respond to such conditions determines the survival and ...
Ceramide induces a multicomponent intracellular calcium increase triggering the acrosome secretion in human sperm
(Elsevier Science, 2020-07)
Exocytosis of spermatozoon's secretory vesicle, named acrosome reaction (AR), is a regulated event that plays a central role in fertilization. It is coupled to a complex calcium signaling. Ceramide is a multitasking lipid ...
Calcium intake and health
(Multidisciplinary Digital Publishing Institute, 2019-07-15)
There are striking inequities in calcium intake between rich and poor populations. Appropriate calcium intake has shown many health benefits, such as reduction of hypertensive disorders of pregnancy, lower blood pressure ...
Capacitative calcium entry in testosterone-induced intracellular calcium oscillations in myotubesJOURNAL OF ENDOCRINOLOGYJ ENDOCRINOL
(SOCIETY FOR ENDOCRINOLOGY, 2017)
Deterministic Limit of Intracellular Calcium Spikes
(American Physical Society, 2019-02)
In nonexcitable cells, global Ca2+ spikes emerge from the collective dynamics of clusters of Ca2+ channels that are coupled by diffusion. Current modeling approaches have opposed stochastic descriptions of these systems ...
Rapid nongenomic effects of 3,5,3′-triiodo-L-thyronine on the intracellular pH of L-6 myoblasts are mediated by intracellular calcium mobilization and kinase pathways
(Endocrine Society, 2004-12)
L-T3 and L-T4 activated the Na+/H + exchanger of L-6 myoblasts, with a fast nongenomic mechanism, both in the steady state and when cells undergo acid loading with ammonium chloride. Monitored with the intracellular ...
Mechanisms involved in the relationship between low calcium intake and high blood pressure
(Molecular Diversity Preservation International, 2019-05)
There is increasing epidemiologic and animal evidence that a low calcium diet increases blood pressure. The aim of this review is to compile the information on the link between low calcium intake and blood pressure. Calcium ...
Intracellular Ca2+ oscillations generated via the extracellular Ca2+-sensing receptor (CaSR) in response to extracellular Ca2+ or l-phenylalanine: Impact of the highly conservative mutation Ser170Thr
(Academic Press Inc Elsevier Science, 2015-11)
The extracellular Ca2+-sensing receptor (CaSR) is an allosteric protein that responds to changes in the extracellular concentration of Ca2+ ([Ca2+]e) and aromatic amino acids with the production of different patterns of ...
Using two dyes to observe the competition of Ca2+ trapping mechanisms and their effect on intracellular Ca2+ signals
(IOP Publishing, 2018-08)
The specificity and universality of intracellular Ca2+ signals rely on the variety of spatio-temporal patterns that the Ca2+ concentration can display. Ca2+ liberation through inositol 1,4,5-trisphosphate receptors (IP3Rs) ...
Cardiac basal metabolism: Energetic cost of calcium withdrawal in the adult rat heart
(Wiley Blackwell Publishing, Inc, 2010-07)
Aim: Cardiac basal metabolism upon extracellular calcium removal and its relationship with intracellular sodium and calcium homeostasis was evaluated. Methods: A mechano-calorimetric technique was used that allowed the ...