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Genetic polymorphisms in the Interleukins IL1B, IL4, and IL6 are associated with concomitant periodontitis and type 2 diabetes mellitus in Brazilian patients
(2020-01-01)
Objective: To assess whether single nucleotide polymorphisms (SNPs) in the IL10, IL1A, IL1B, IL4, TNFA, IL6, OPG, RANK, and RANKL genes, “classically” related with periodontitis, could be associated with susceptibility to ...
Interleukin-1 beta and Interleukin-6 Expression and Gene Polymorphisms in Subjects with Peri-Implant Disease
(Wiley-Blackwell, 2012-12-01)
Background: Polymorphisms found in the IL-1 family genes have been associated with susceptibility of periodontal disease. However, very little is known about the relationship between polymorphisms on inflammatory mediators' ...
Interleukin-10 but not interleukin-18 may be associated with the immune response against well-differentiated thyroid cancer
(Hospital Clinicas, Univ Sao PauloSao PauloBrasil, 2011)
Associação entre carga proviral e polimorfismos dos genes IL-6 e IL-10 na infecção pelo HTLV-1
(Sociedade Brasileira de Medicina Tropical, 2019)
Interleukin-15 in gene therapy of cancer
(Bentham Science Publishers, 2013-02)
Interleukin-15 (IL-15) exerts powerful stimulatory effects on lymphocyte subsets that result in antiviral and antitumoral activities. The functions of this cytokine are mainly mediated in a cell-to-cell contact fashion ...
Molecular mechanisms of the induction of IL-12 and its inhibition by IL- 10
(1998-06-15)
Exogenously added IL-10 rapidly inhibited Staphylococcus aureus- or LPS- induced cytokine mRNA expression in human PBMCs and monocytes, with a maximal effect observed when IL-10 was added from 20 h before until 1 h after ...
High interleukin-4 expression and interleukin-4 gene polymorphisms are associated with susceptibility to human paracoccidioidomycosis
(Fundaco Oswaldo Cruz, 2015-09-01)
Paracoccidioidomycosis (PCM) is caused by dimorphic fungi from the Paracoccidioides brasiliensis complex. Previous studies have demonstrated that the severity of disease is associated with a T-helper 2 immune response ...
Molecular mechanisms of the induction of IL-12 and its inhibition by IL- 10
(1998-06-15)
Exogenously added IL-10 rapidly inhibited Staphylococcus aureus- or LPS- induced cytokine mRNA expression in human PBMCs and monocytes, with a maximal effect observed when IL-10 was added from 20 h before until 1 h after ...
Cytokine gene variants and venous thrombotic risk in the BRATROS (BRAZILIAN THROMBOSIS STUDY)
(2007-05-21)
Introduction: Venous thrombosis (VT) and inflammation are two closely related entities. In the present investigation we assessed whether there is a relation between genetic modifiers of the inflammatory response and the ...