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PRP8 intein in Ajellomycetaceae family pathogens: Sequence analysis, splicing evaluation and homing endonuclease activity

Universidade Estadual Paulista (Unesp); Dalhousie Univ (Academic Press Inc. Elsevier B.V., 2011-02-01)

Inteins are intervening sequences that are transcribed and translated with flanking host protein sequences and then self-excised by protein splicing. Bi-functional inteins also contain a homing endonuclease responsible for ...

Inteins in pathogenic fungi: a phylogenetic tool and perspectives for therapeutic applications

Universidade Estadual Paulista (Unesp) (Instituto Oswaldo Cruz, Ministério da Saúde, 2009-05-01)

Inteins or internal proteins are coding sequences that are transcribed and translated with flanking sequences (exteins). After translation, the inteins are excised by an autocatalytic process and the host protein assumes ...

PRP8 intein in cryptic species of Histoplasma capsulatum: Evolution and phylogeny

Universidade Federal do Rio Grande do Norte (UFRN); Centers for Disease Control and Prevention (CDC); United States Dept. of Agriculture-Agricultural Research Service (USDA-ARS); Universidade Estadual Paulista (Unesp) (2013-08-01)

The PRP8 intein is the most widespread intein among the Kingdom Fungi. This genetic element occurs within the prp8 gene, and is transcribed and translated simultaneously with the gene. After translation, the intein excises ...

Phylogenetic analysis of PRP8 intein in Paracoccidioides brasiliensis species

Universidade Estadual Paulista (Unesp) (Academic Press Inc. Elsevier B.V., 2008-09-01)

A recent species status investigation of the pathogenic fungus Paracoccidioides brasiliensis suggested the existence of three cryptic species. In the present study the sequences of the PRP8 intein from A brasiliensis ...

Analysis of inteins in the Candida parapsilosis complex for simple and accurate species identification

Universidade Estadual Paulista (Unesp); Universidade Federal do Rio Grande do Norte (UFRN); Centers for Disease Control and Prevention (2013-09-01)

Inteins are coding sequences that are transcribed and translated with flanking sequences and then are excised by an autocatalytic process. There are two types of inteins in fungi, mini-inteins and full-length inteins, both ...

Genus Paracoccidioides: Species Recognition and Biogeographic Aspects

Universidade Estadual Paulista (Unesp); Universidade de Brasília (UnB); Ctr Microbiol & Cell Biol (Public Library Science, 2012-05-30)

Background: Paracoccidioidomycosis is a systemic mycosis caused by Paracoccidioides brasiliensis (species S1, PS2, PS3), and Paracoccidioides lutzii. This work aimed to differentiate species within the genus Paracoccidioides, ...