Search
Now showing items 1-10 of 6490
Protein deficiency and nutritional recovery modulate insulin secretion and the early steps of insulin action in rats
(1998-10-01)
Maternal malnutrition was shown to affect early growth and leads to permanent alterations in insulin secretion and sensitivity of offspring. In addition, epidemiological studies showed an association between low birth ...
Análogos de insulina: en búsqueda del reemplazo fisiológico
(Sociedad Médica de Santiago, 2006)
Insulin analogues: Searching for a physiological replacement Análoges de insulina: En búsqueda del reemplazo fisiológico
(2006)
Insulin analogues, developed by molecular engineering, have structural changes in the A and B insulin chains. These modifications change their action profile, rendering insulin replacement closer to physiology. Rapid acting ...
Effects of fluoride intake on insulin sensitivity and insulin signal transduction
(Int Soc Fluoride Research, 2008-10-01)
Forty seven-week-old male castrated Wistar rats were randomly divided evenly into a control group and a fluoride (F) group. The latter was given a single dose of NaF from a solution containing 1.0 mg F ion/kg bw, administered ...
Effects of fluoride intake on insulin sensitivity and insulin signal transduction
(Int Soc Fluoride Research, 2013)
Insulin secretion, insulin sensitivity, and hepatic insulin extraction in first-degree relatives of type 2 diabetic patients
(Associação Brasileira de Divulgação Científica (ABRADIC), 2003-03-01)
To identify early metabolic abnormalities in type 2 diabetes mellitus, we measured insulin secretion, sensitivity to insulin, and hepatic insulin extraction in 48 healthy normal glucose-tolerant Brazilians, first-degree ...
Glucose- and insulin-induced phosphorylation of the insulin receptor and its primary substrates IRS-1 and IRS-2 in rat pancreatic islets
(Elsevier B.V., 1995-12-27)
The presence of tyrosine-phosphorylated proteins was studied in cultured rat pancreatic islets, Immunoblotting performed with total extracts of islets cultured in the presence of 1.8 or 5.6 mM glucose revealed at least ...