Now showing items 1-10 of 28
Innate immune cells' contribution to systemic lupus erythematosus
(Frontiers Media S.A., 2019)
Copyright © 2019 Herrada, Escobedo, Iruretagoyena, Valenzuela, Burgos, Cuitino and Llanos.Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by the presence of autoantibodies against nuclear ...
Obesity And Asthma: Beyond T(h)2 Inflammation
(W B SAUNDERS CO-ELSEVIER INCPHILADELPHIA, 2015)
An approach to local immunotoxicity induced by adjuvanted vaccines
The occurrence of injection site reactions following immunization is the most frequently reported toxicity manifestation of vaccines; however, the different types of local reactions and the different mechanisms involved ...
Innate immune cells for immunotherapy of autoimmune and cancer disorders
Modulation of the immune system has been widely targeted for the treatment of several immune-related diseases, such as autoimmune disorders and cancer, due to its crucial role in these pathologies. Current available therapies ...
CCR6 and NK1.1 distinguish between IL-17A and IFN-γ-producing γδ effector T cells
γδ T cells are a potent source of innate IL-17A and IFN-γ, and they acquire the capacity to produce these cytokines within the thymus. However, the precise stages and required signals that guide this differentiation are ...
CD169 + macrophages orchestrate innate immune responses by regulating bacterial localization in the spleen
(American Association for the Advancement of Science, 2017-10)
The spleen is an important site for generating protective immune responses against pathogens. After infection, immune cells undergo rapid reorganization to initiate and maintain localized inflammatory responses; however, ...
Tumor immune escape mechanisms that operate during metastasis
(Bentham Science Publishers, 2011-04)
Immune cells actively influence, among other factors, each step of tumor development determining the chance of a cancer cell to survive in a threaten microenvironment. Antitumor immune-mediated mechanisms are activated as ...
Effects of dietary restriction or swimming on lymphocytes and macrophages functionality from old rats
(Informa HealthcareLondonInglaterra, 2014)
A novel function for galectin-1 at the crossroad of innate and adaptive immunity: galectin-1 regulates monocyte/macrophage physiology through a nonapoptotic ERK-dependent pathway
(American Association of Immunologists, 2007-01-01)
Several environmental factors can differentially regulate monocyte and macrophage response patterns, resulting in the display of distinct functional phenotypes. Galectin-1, an endogenous lectin found at peripheral lymphoid ...