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Proteinase inhibitor accumulation in aphid-infested barley leaves
(1998)
Proteinase inhibitors (chymotrypsin and trypsin inhibitors) accumulation in barley leaves was studied when the plants were infested with the aphids Schizaphis graminum and Rhopalosiphum padi. Aphid infestation resulted ...
Nuclear and kinetoplast DNA synthesis in Trypanosoma cruzi, autoradiographical study with DNA polymerase inhibitors
(1993)
DNA synthesis in epimastigote forms of Trypanosoma cruzi was studied autoradiographically by incorporation of [3H]thymidine in the nuclear and kinetoplast DNA. Both DNA were heavily labelled. Three eukaryotic DNA polymerase ...
Cell proliferation and tumor formation induced by eserine, an acetylcholinesterase inhibitor, in rat mammary gland
(2007)
Environmental chemicals may be involved in the etiology of breast cancer. There is substantial evidence that breast cancer risk is associated with prolonged exposure to female hormones. Among these hormonal influences a ...
The economic impact of introducing serotonin-noradrenaline reuptake inhibitors into the Brazilian national drug formulary: Cost-effectiveness and budget-impact analyses
(Adis International Ltd, 2007)
Objective: To determine the cost effectiveness, from the Brazilian Ministry of Health viewpoint, of three antidepressant classes for major depressive disorder (MDD), and the budget impact of introducing serotonin-noradrenaline ...
The advantages of polymeric hydrogels in calcineurin inhibitor delivery
(MDPI, 2020)
In recent years, polymeric hydrogels (PolyHy) have been extensively explored for their applications in biomedicine as biosensors, in tissue engineering, diagnostic processes, and drug release. The physical and chemical ...
A protein inhibitor of calmodulin-regulated cyclic nucleotide phosphodiesterase in amphibian ovaries
(1985)
The cytosol fraction of an extract of Xenopus laevis ovaries contains a protein inhibitor that can specifically block the activation of calmodulin-sensitive cyclic nucleotide phosphodiesterase (PDE I) found in that tissue. ...
Caspase inhibitor attenuates the shape changes in the alveolar ridge following tooth extraction: a pilot study in rats
(Wiley, 2020)
Objective The aim of the study was to determine whether the inhibition of apoptosis via pan-caspase inhibitors can attenuate the changes in the alveolar ridge upon tooth extraction. Background Cells undergoing apoptosis ...
2-Arylthiomorpholine derivatives as potent and selective monoamine oxidase B inhibitors
(2010)
2-Arylthiomorpholine and 2-arylthiomorpholin-5-one derivatives, designed as rigid and/or non-basic phenylethylamine analogues, were evaluated as rat and human monoamine oxidase inhibitors. Molecular docking provided insight ...
Topical carbonic anhydrase inhibitors in macular edema associated with Alstrom syndrome
(Taylor & Francis, 2016)
Background: Alstrom syndrome is a rare genetic ciliopathy caused by a mutation in the ALMS1 gene. The syndrome is characterized by cone-rod dystrophy, dilated myocardiopathy, childhood obesity and sensorineural hearing ...
Oncogenic ras protein induces meiotic maturation of amphibian oocytes in the presence of protein synthesis inhibitors
(1988)
Microinjection of the activated ras oncogenic protein can induce the meiotic maturation of Xenopus laevis oocytes, a process that can also be triggered by progesterone or high concentrations of insulin. Cycloheximide and ...