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The role of test context in latent inhibition of conditioned inhibition: Part of a search for general principles of associative interference
(Springer, 2015)
In two lick suppression experiments with rats, we assessed interference with behavior indicative of conditioned inhibition by a latent inhibition treatment as a function of test context. We asked what effect the test context ...
Proactive interference by cues presented without outcomes: Differences in context specificity of latent inhibition and conditioned inhibition
(Springer, 2018)
This report is part of a larger project examining associative interference as a function of the nature of the interfering and target
associations. Lick suppression experiments with rats assessed the effects of context ...
Complex mitochondrial dysfunction induced by TPP+-gentisic acid and mitochondrial translation inhibition by doxycycline evokes synergistic lethality in breast cancer cells
(MDPI, 2020)
The mitochondrion has emerged as a promising therapeutic target for novel cancer treatments because of its essential role in tumorigenesis and resistance to chemotherapy. Previously, we described a natural compound, ...
MAO inhibition by arylisopropylamines: the effect of oxygen substituents at the b-position
(Elsevier Ltd., 2004-05-26)
Abstract—Twenty-nine arylisopropylamines, substituted at the b-position of their side chain by an oxo, hydroxy, or methoxy group,
were evaluated in vitro as MAO-A and MAO-B inhibitors. The oxo derivatives (‘cathinones’) ...
Treatment of oocyte membranes with the 2',3'-dialdehyde of guanosine triphosphate reduces progesterone inhibition of adenylyl cyclase
(1985)
Treatment of Xenopus laevis membranes with the 2',3'-dialdehyde of GTP (dial GTP) drastically inhibits their adenylyl cyclase activity. Optimal inhibition is obtained by treatment with 1 mM dial GTP for Ih at 32°C. Using ...
Extinction training can make the extinction context a stimulusspecific inhibitor: a potential mechanism of experimental renewal
(Elsevier, 2020)
Renewal is the recovery of extinguished responding to a conditioned stimulus when testing occurs outside the extinction context. Renewal has been explained as the extinction context becoming a negative occasion setter ...
Effect of mitochondrial complex I inhibition on Fe-S cluster protein activity
(2011)
Iron-sulfur (Fe-S) clusters are small inorganic cofactors formed by tetrahedral coordination of iron atoms with sulfur groups. Present in numerous proteins, these clusters are involved in key biological processes such as ...
Studies on the mechanism of inhibition of amphibian oocyte adenylate cyclase by progesterone
(1984)
Progesterone treatment induces the meiotic maturation of Xenopus laevis oocytes. Previous evidence indicates that this hormonal effect may be due to inhibition of oocyte adenylate cyclase. The present work studies several ...
A theoretical study of the inhibition of human 4-hydroxyphenylpyruvate dioxygenase by a series of pyrazalone-quinazolone hybrids
(Scholars Research Library, 2016)
A Density Functional Theory study was carried out to find relationships between the electronic/molecular structure of a group of pyrazalone-quinazolone hybrids and their inhibition of human 4-hydroxyphenylpyruvate dioxygenase ...
Autophosphorylation of carboxy-terminal residues inhibits the activity of protein kinase CK1α
(2009)
CK1 constitutes a protein kinase subfamily that is involved in many important physiological processes. However, there is limited knowledge about mechanisms that regulate their activity. Isoforms CK1δ and CKlε were previously ...