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Polymorphisms in p1-p6/p6* of HIV Type 1 Can Delay Protease Autoprocessing and Increase Drug Susceptibility
(Mary Ann Liebert, 2003-09)
Maturation of infectious human immunodeficiency virus type 1 (HIV-1) particles requires proteolytic cleavage of structural polyproteins by viral protease. Inhibition of protease is a powerful tool for the treatment of HIV ...
Defense response of susceptible and resistant Biomphalaria alexandrina snails against Schistosoma mansoni infection
(Universidad de Costa Rica, 2012)
Cardiovascular Reactivity to a Novel Stressor: Differences on Susceptible and Resilient Rats to Social Defeat Stress
(2022-02-16)
Prolonged and heightened responses to stress are known factors that influence the development of mood disorders and cardiovascular diseases. Moreover, the coping strategies related to the experience of adverse events, i.e., ...
Antimicrobial susceptibility of salmonella gallinarum and salmonella pullorum isolated from ill poultry in brazilSuscetibilidade a antimicrobianos de Salmonella Gallinarum e Salmonella Pullorum isolados de aves doentes no Brasil
(2016-03-01)
Salmonella Gallinarum (S. Gallinarum) and Salmonella Pullorum (S. Pullorum) are poultry host-specific, agents of fowl typhoid and pullorum disease, respectively. These biovars cause septicemic infections, resulting in high ...
Inactivation of glutamine synthetase-coding gene glnA increases susceptibility to quinolones through increasing outer membrane protein F in salmonella enterica serovar typhi
(Frontiers Media, 2020)
Ciprofloxacin is the choice treatment for infections caused by Salmonella Typhi, however, reduced susceptibility to ciprofloxacin has been reported for this pathogen. Considering the decreased approbation of new antimicrobials ...
The Cefazolin Inoculum Effect Is Associated With Increased Mortality in Methicillin-Susceptible Staphylococcus aureus Bacteremia
(Oxford University Press, 2018)
Background: Recent studies have favored the use of cefazolin over nafcillin for the treatment of methicillin-susceptible Staphylococcus aureus (MSSA) bacteremia. The clinical influence of the cefazolin inoculum effect ...
Antimicrobial susceptibility of strains of Propionibacterium acnes isolated from inflammatory acne
(2006)
In the last decade, a significant increase in the antimicrobial resistance of clinical specimens of Propionibacterium acnes to first line antibiotics used for acne treatment, has been informed in Europe and in the USA. No ...
Direct determination of pyrazinamide (PZA) susceptibility by sputum microscopic observation drug susceptibility (MODS) culture at neutral pH: the MODS-PZA assay
(American Society for Microbiology, 2020)
Pyrazinamide (PZA) is considered the pivot drug in all tuberculosis treatment regimens, due to its particular action on the persistent forms of Mycobacterium tuberculosis. However, no drug susceptibility test (DST) is ...