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Immune response to glutaraldehyde-treated cells. I. Dissociation of immunological memory and antibody production
(1979)
Glutaraldehyde (GA)-treated sheep red blood cells (SRBC) or H-2 allogeneic spleen cells (SC), induced immunological memory with absent or markedly reduced primary antibody production. In contrast, a normal secondary response ...
DL-2-hydroxyisocaproic acid attenuates inflammatory responses in a murine Candida albicans biofilm model
(2014)
Chronic biofilm infections are often accompanied by a chronic inflammatory response, leading to impaired healing and increased, irreversible damage to host tissues. Biofilm formation is a major virulence factor for Candida ...
Tumour necrosis factor (TNF)α -308 G/G promoter polymorphism and TNFα levels correlate with a better response to adalimumab in patients with rheumatoid arthritis
(2006)
Objective: To investigate the influence of -308 tumour necrosis factor-α (TNFα) promoter polymorphism and circulating TNFα levels in the clinical response to adalimumab treatment in patients with rheumatoid arthritis (RA). ...
Biochemical, immunological, and biological characterization of trypanosoma cruzi populations of the andean North of Chile
(1995)
Twenty-one Trypanosoma cruzi stocks isolated from Triatoma infestans and humans of the Chilean Andean highlands were studied at the genotypic level by schizodeme and molecular karyotype analyses, which allowed a clear ...
Tumour necrosis factor-α (TNF-α) levels and influence of -308 TNF-α promoter polymorphism on the responsiveness to infliximab in patients with rheumatoid arthritis
(2004)
Objective: To investigate the influence of -308 tumour necrosis factor-α (TNF-α) promoter polymorphism and circulating TNF-α levels in the clinical response to the infliximab treatment in patients with rheumatoid arthritis ...
Local and systemic specific antibody response of different chicken lines after ocular vaccination against infectious bronchitis
(1996)
The specific lacrimal fluid IgA levels and the specific serum IgG levels of broiler chicks (meat type hybrids (MT)), brown-egg layer chicks (heavy layer (HL)), and white leghorn chicks (light layer (LL)) were compared after ...
Intradermal DNA electroporation induces survivin-specific CTLs, suppresses angiogenesis and confers protection against mouse melanoma
(2010)
Survivin is an intracellular tumor-associated antigen that is broadly expressed in a large variety of tumors and also in tumor associated endothelial cells but mostly absent in differentiated tissues. Naked DNA vaccines ...
Interleukin-4 Selectively Inhibits Interleukin-2 Secretion by Lipopolysaccharide-Activated Dendritic Cells
(2004)
Dendritic cells (DCs) generated in vitro from bone marrow precursors using
granulocyte-macrophage colony-stimulating factor (GM-CSF) secrete interleukin-2
(IL-2) upon activation, an event probably associated to the ...
Kinetics of immune responses in deer mice experimentally infected with sin nombre virus
(2012)
Deer mice are the principal reservoir hosts of Sin Nombre virus, the etiologic agent of most hantavirus cardiopulmonary syndrome cases in North America. Infection of deer mice results in persistence without conspicuous ...
RESETing ER proteostasis: Selective stress pathway hidden in the secretory route
(Wiley-VCH Verlag, 2014)
The efficient folding of membrane and
secreted proteins relies on the unfolded
protein response (UPR) to buffer fluctuations in the load of misfolded proteins.
Although the UPR is thought to operate on
a generic manner ...