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Multiple Tolerization Reduces Antibody Binding Against Tolerogen Cells: Implications for the Production of Monoclonal Antibodies
(2018-04-01)
We report an immunization technique that can update the production of monoclonal antibodies (mAbs): the multiple tolerization subtractive immunization (MTSI). A total of 10 BALB/C mice were used. Animals in group 1 received ...
Inhibition of the hemorrhagic activity of Bothrops asper venom by a novel neutralizing mixture
(1997-06)
This study screened 25 sera, 19 synthetic products and five antivenoms obtained after immunization for their ability to neutralize the hemorrhagic activity of venom from the snake Bothrops asper. Among the sera screened, ...
Dissociation of enzymatic and toxic activities by the use of antibodies
(1990)
IN
A
RECENT
article
KASTURi
and
GOWDA,(1990)
described
the
dissociation
of
enzymatic
and
toxic
activities
of
phospholipases
A,
(PLA)
from
Vipera
russelli
venom
by
neutraliza-
tion
experiments
u ...
Antibody-mediated neutralization and binding-reversal studies on α-neurotoxins from micrurus nigrocinctus nigrocinctus (coral snake) venom
(1996-03)
An ELISA based, non-radioactive acetylcholine receptor (AchR) binding assay was used to detect the alpha-neurotoxins present in Micrurus nigrocinctus nigrocinctus venom. Sera from horses hyperimmunized against M. nigrocinctus ...
Protection against high-dose homologous infection in calves immunized with intestine or membrane extracts from Haemonchus placei
(ELSEVIER SCIENCE BV, 2008)
Control of Haemonchus placei, one of the most important cattle nematodes in Brazil, relies on the use of anthelmintics. However, there is a need for integrated control, which includes active immunization. The aim of this ...
Modulation of mucosal immunity in a murine model of food-induced intestinal inflammation
(BLACKWELL PUBLISHING, 2008)
Background Hypersensitivity or uncontrolled responses against dietary antigens can lead to inflammatory disorders like food allergy and current models reflect a variety of causes but do not reveal the detailed modulation ...
Humoral immune response in dogs and cats vaccinated against rabies in southeastern Brazil
(Biomed Central Ltd., 2013-07-30)
Background: Brazil holds annual nationwide public campaigns to vaccinate dogs and cats against rabies. The presence of rabies antibodies in these animals, which are among the main transmitters of rabies to humans, is a ...
Detection of the 43,000-molecular-weight glycoprotein in sera of patients with paracoccidioidomycosis
(1989-12-09)
The 43,000-molecular-weight (43K) soluble glycoprotein was detected in sera of patients with paracoccidioidomycosis by the immunoblot technique by using as the probe rabbit monospecific antisera to this fraction. The 43K ...
In vitro evidence for immune evasion activity by human plasmin associated to pathogenic Leptospira interrogans
(ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD, 2011)
Leptospirosis is a widespread re-emerging zoonosis of human and veterinary concern. It has been shown that virulent leptospires protect themselves against the host`s innate immune system, a strategy that allows the bacteria ...
Western blot analysis of tick antigens from a Rhipicephalus sanguineus unfed larval extract and identification of antigenic sites in tick sections using immunohistochemistry. A comparative study between resistant and susceptible host species
(1996-03-01)
Most parasite-host relationships are characterized by the development of resistance by the host, thus limiting the number of parasites. However, some cases are very unusual. In the relationship of the domestic dog with the ...