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Mucopolysaccharidosis type II: identification of 30 novel mutations among Latin American patients
(Elsevier, 2014)
In this study, 103 unrelated South-American patients with mucopolysaccharidosis type II (MPS II) were investigated aiming at the identification of iduronate-2-sulfatase (IDS) disease causing mutations and the possibility ...
Mucopolysaccharidosis type II: Identification of 30 novel mutations among Latin American patients
(Academic Press Inc Elsevier ScienceSan DiegoEUA, 2014)
Anaerobic sulfatase maturase AslB from Escherichia coli activates human recombinant iduronate-2-sulfate sulfatase (IDS) and N-acetylgalactosamine-6-sulfate sulfatase (GALNS)
Maturation of type I sulfatases requires the conversion of the cysteine (Cys) or serine (Ser) present in the active site to formylglycine (FGly). This activation represents a limiting step during the production of recombinant ...
Mucopolysaccharidosis type II: Identification of 30 novel mutations among Latin American patients
(Elsevier, 2014)
In this study, 103 unrelated South-American patients with mucopolysaccharidosis type II (MPS II) were investigated aiming at the identification of iduronate-2-sulfatase (IDS) disease causing mutations and the possibility ...
Iduronate-2-sulfatase interactome: validation by yeast two-hybrid assay
(2022)
Mucopolysaccharidosis type II (MPS II), also known as Hunter syndrome, is a rare X-linked recessive disease caused by a deficiency of the lysosomal enzyme iduronate-2-sulfatase (IDS), which activates intracellular accumulation ...
Human sulfatase transiently and functionally active expressed in E. coli K12
(Pontificia Universidad Católica de Valparaíso, 2010)