Now showing items 1-10 of 58673
Estudo das interleucinas pró-inflamatórias (IL-2, IL-2R, IL-6, IL-6R, IL-8 e IL-12) e Anti-Inflamatórias (IL-4, IL-4R e IL-10) no carcinoma diferenciado da tiroideAnalysis of pro-inflammatory interleukins (IL-2, IL-2R, IL-6, IL-6R, IL-8 and IL-12) and anti-inflammatory interleukins (IL-4, IL-4R and IL-10) in the differentiated thyroid cancer
Interleukin 4 induces the expression of inducible nitric oxide synthase in eosinophils
(Elsevier B.V., 2005-05-07)
We investigated the effects of the Th-2-like cytokines IL-4 and IL-13 and of IL-10 on the induction of iNOS and NO production in rat eosinophils. Addition of mIL-4 to the eosinophil culture increased iNOS activity and ...
Imbalance of IL-2, IFN-gamma and IL-10 secretion in the immunosuppression associated with human paracoccidioidomycosis
(W B Saunders Co, 2001-02-21)
Patients with paracoccidioidomycosis (PCM) display a certain degree of immunecompromise characterized by lymphocyte hyporesponsiveness to the main Paracoccidioides brasiliensis antigen (gp43). To determine whether cytokines ...
Investigação dos polimorfismos dos genes da interleucina-1 (IL-1), IL1RN, IL-4, IL-6 e IL-10 em pacientes adultos portadores de púrpura trombocitopênica imune = Investigation of interleukin-1 (IL-1), IL1RN, IL-4, IL-6 and IL-10 gene polymorphism adult patients with immune thrombocytopenic purpuraInvestigation of interleukin-1 (IL-1), IL1RN, IL-4, IL-6 and IL-10 gene polymorphism adult patients with immune thrombocytopenic purpura
Interleukin-15 augments oxidative metabolism and fungicidal activity of human monocytes against Paracoccidioides brasiliensis
(Instituto Oswaldo Cruz, Ministério da Saúde, 2010-11-01)
Interleukin (IL)-15 is a pleiotropic cytokine that regulates the proliferation and survival of many cell types. IL-15 is produced by monocytes and macrophages against infectious agents and plays a pivotal role in innate ...
Prostaglandin mediates IL-23/IL-17-induced neutrophil migration in inflammation by inhibiting IL-12 and IFN gamma production
(NATL ACAD SCIENCES, 2009)
IL-23/IL-17-induced neutrophil recruitment plays a pivotal role in rheumatoid arthritis (RA). However, the mechanism of the neutrophil recruitment is obscure. Here we report that prostaglandin enhances the IL-23/IL-17-induced ...
Association between genetic polymorphisms of interleukin 6 (IL6), IL6R and IL18 with metabolic syndrome in obese Chilean children Polimorfismos genéticos de interleuquina 6 (IL6), IL6R e IL18: Asociación con componentes del síndrome metabólico en niños ch
(Sociedad Medica de Santiago, 2014)
Background: Metabolic Syndrome (MS) is highly prevalent among obese children and adolescents and is considered a predictor for the development of type 2 diabetes mellitus and cardiovascular disease. Obesity is associated ...
Crystal structure of the IL-22/IL-22R1 complex and its implications for the IL-22 signaling mechanism
(ELSEVIER SCIENCE BV, 2008)
Interleukin-22 (IL-22) is a member of the interleukin-10 cytokine family, which is involved in anti-microbial defenses, tissue damage protection and repair, and acute phase responses. Its signaling mechanism involves the ...
Crystal structure of a soluble decoy receptor IL-22BP bound to interleukin-22
(ELSEVIER SCIENCE BV, 2009)
Interleukin-22 (IL-22) plays an important role in the regulation of immune and inflammatory responses in mammals. The IL-22 binding protein (IL-22BP), a soluble receptor that specifically binds IL-22, prevents the ...