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Efficient isolation and proliferation of human adipose-derived mesenchymal stromal cells in xeno-free conditions

Universidade de São Paulo (USP); Institute of Medical-Hospital Service (IAM); São Lucas – Cell Therapy Group; Universidade Estadual Paulista (Unesp) (2020-04-01)

Classical methods used for culture of adipose-derived mesenchymal stromal cells (ADSCs) use xenobiotic components, which may present a potential risk for biological contamination and/or elicit immunological reactions. ...

The increased expression of receptor activator of nuclear-κB ligand (RANKL) of multiple myeloma bone marrow stromal cells is inhibited by the bisphosphonate ibandronate

Fernández, Mireya; Pino, Ana M.; Figueroa, Paula; Rodríguez, Juan P. (2010)

The receptor activator of nuclear factor-kappaB ligand (RANKL) and interleukin-1beta are osteoclast activating factors which are abnormally expressed in bone marrow stromal cells and plasma cells of multiple myeloma patients. ...

Neuroprotective effects of human umbilical cord mesenchymal stromal cells in an immunocompetent animal model of Parkinson's disease

Mathieu, Patricia Andrea; Roca, Valeria Ines; Gamba, Cecilia; del Pozo, Ana; Pitossi, Fernando Juan (Elsevier Science, 2012-05)

Microglial activation in the substantia nigra (SN) is a ubiquitous feature in PD which could mediate toxic effects. Human mesenchymal stromal cells (hMSCs) possess immunomodulatory properties. We evaluated whether the ...

Stem Cells: Potential Therapeutics For Periodontal Regeneration.

Silvério, Karina Gonzales; Benatti, Bruno Braga; Casati, Márcio Zaffalon; Sallum, Enílson Antônio; Nociti, Francisco Humberto (2008)

Human Multipotent Mesenchymal Stromal Cells from Distinct Sources Show Different In Vivo Potential to Differentiate into Muscle Cells When Injected in Dystrophic Mice

VIEIRA, N. M.; ZUCCONI, E.; BUENO JR., C. R.; SECCO, M.; SUZUKI, M. F.; BARTOLINI, P.; VAINZOF, M.; ZATZ, M. (SPRINGER HEIDELBERG, 2010)

Limb-girdle muscular dystrophies are a heterogeneous group of disorders characterized by progressive degeneration of skeletal muscle caused by the absence or deficiency of muscle proteins. The murine model of Limb-Girdle ...

Mesenchymal stem cells and their use in therapy: What has been achieved?

Fernández Vallone, Valeria Beatriz; Romaniuk, Maria Albertina; Choi, H.; Labovsky, Vivian; Otaegui, Julian; Chasseing, Norma Alejandra (Elsevier, 2013-01-31)

The considerable therapeutic potential of human multipotent mesenchymal stromal cells or mesenchymal stem cells (MSCs) has generated increasing interest in a wide variety of biomedical disciplines. Nevertheless, researchers ...

Histone deacetylase inhibition destabilizes the multi-potent state of uncommitted adipose-derived mesenchymal stromal cells

Autor desconocido (2014)

Human adipose‐derived mesenchymal stromal cells (AMSCs) grown in platelet lysate are promising agents for therapeutic tissue regeneration. Here, we investigated whether manipulation of epigenetic events by the clinically ...

Human mesenchymal stromal cells in adhesion to cell-derived extracellular matrix and titanium: comparative kinome profile analysis

Erasmus MC; Universidade Estadual Paulista (Unesp) (Wiley-Blackwell, 2018-11-01)

Simvastatin modulates mesenchymal stromal cell proliferation and gene expression

Zanette, Dalila Lucíola; Lorenzi, Julio Cesar Cetrulo; Panepucci, Rodrigo Alexandre; Palma, Patricia Vianna Bonini; Santos, Daiane Fernanda dos; Prata, Karen Lima; Silva, Wilson Araújo (Public Library of Science, 2017)

IL-8, GRO and MCP-1 produced by hepatocellular carcinoma microenvironment determine the migratory capacity of human bone marrow-derived mesenchymal stromal cells without affecting tumor aggressiveness

Bayo J.; Real A.; Fiore E.J.; Malvicini M.; Sganga L.; Bolontrade M.; Andriani O.; Bizama C.; Fresno C.; Podhajcer O.; Fernandez E.; Gidekel M.; Mazzolini G.D.; García M.G. (Impact Journals LLC, 2017)

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