Now showing items 1-10 of 239
Cytogenetic evaluation of 20 primary breast carcinomas
Chromosome analysis was performed on samples from 20 Brazilian patients with breast cancer. All the samples were from untreated patients who presented the clinical symptoms for months or years before surgical intervention. ...
Interstitial long-arm deletion of chromosome 7 and ectrodactyly
An interstitial deletion of 7q21 was found in a boy with mental retardation, microcephaly, convergent strabismus, micrognathia, genital anomalies, and other findings, including ectrodactyly.
Velocardiofacial syndrome with a rare t(2;22)
Rearrangements involving chromosomes 2 and 22 were described not only as acquired abnormalities in a variety of human neoplasias but also in the constitutional karyotype suggesting the existence of a greater fragility in ...
Clonal chromosome abnormalities found in three non-neoplastic proliferative brain lesions
Chromosome analysis was made of brain lesions from three patients which, according to classical histopathological criteria, did not contain tumor cells. In addition to normal cells, we identified abnormal karyotypes with ...
Tetrasomy 15Q11-Q13 identified by fluorescence in situ hybridization in a patient with autistic disorder
We report a female child with tetrasomy of the 15q11-q13 chromosomal region, and autistic disorder associated with mental retardation, developmental problems and behavioral disorders. Combining classical and molecular ...