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Comparative SCF MO studies for some histamine analogues as agonists of the H2 receptor of histamine
(Sociedad Chilena de Química, 1999)
This paper presents SCF AM1 and CNDO/2 RF calculations of the potential energy surface of histamine monocation (HA) and the agonists 2-(4-thiazolyl)ethylamine (TIA) and 2-(4-oxazolyl)ethylamine (OXA). the similarity of ...
The possible involvement of hyperpolarizing mechanisms in histamine-induced relaxation of the rat portal vein
(2008-11-07)
The present study evaluated the effects of histamine 10 -2 M on longitudinal preparations of rat portal vein. It was observed that histamine 10 -2 M induced relaxation of rat portal vein preparations pre-contracted with ...
The possible involvement of hyperpolarizing mechanisms in histamine-induced relaxation of the rat portal vein
(2008-11-07)
The present study evaluated the effects of histamine 10 -2 M on longitudinal preparations of rat portal vein. It was observed that histamine 10 -2 M induced relaxation of rat portal vein preparations pre-contracted with ...
Involvement of histamine H1 and H2 receptor inverse agonists in receptor's crossregulation
(Elsevier Science, 2019-03)
Histamine [2-(4-Imidazolyl)-ethylamine] modulates different biological processes, through histamine H1 and H2 receptors, and their respective blockers are widely used in treating allergic and gastric acid-related disorders. ...
Histamine therapeutic efficacy in metastatic melanoma : role of histamine H4 receptor agonists and opportunity for combination with radiation
(Impact Journals, 2017)
Abstract: The aims of the work were to improve our knowledge of the role of H4R in melanoma proliferation and assess in vivo the therapeutic efficacy of histamine, clozapine and JNJ28610244, an H4R agonist, in a preclinical ...
Antitumor role of histamine h4 receptor in human t-cell lymphoma: therapeutic benefit for combination therapy with histamine and histone deacetylase inhibitors
(Fundación Revista Medicina, 2019)
The discovery of the human histamine H4 receptor (H4R) has contributed to our understanding of histamine role in numerous physiological and pathological conditions, including tumor development and progression. High histamine ...
Agents that inhibit histamine release: A review
(1992-01-01)
It is well known that histamine is found in high concentration in mast cell granules(1). The histamine content of these granules may be released to the extracellular space if an appropriate stimulus is provided(2). Besides ...
Agents that inhibit histamine release: A review
(1992-01-01)
It is well known that histamine is found in high concentration in mast cell granules(1). The histamine content of these granules may be released to the extracellular space if an appropriate stimulus is provided(2). Besides ...