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Jupyter and Galaxy: Easing entry barriers into complex data analyses for biomedical researchers
(PLoS, 2017)
What does it take to convert a heap of sequencing data into a publishable result? First, common
tools are employed to reduce primary data (sequencing reads) to a form suitable for further
analyses (i.e., the list of ...
A global reference for human genetic variation
(Nature Research, 2015)
The 1000 Genomes Project set out to provide a comprehensive description of common human genetic variation by applying whole-genome sequencing to a diverse set of individuals from multiple populations. Here we report ...
Evaluation of MC1R high-throughput nucleotide sequencing data generated by the 1000 genomes project
(2017-01-01)
The advent of next-generation sequencing allows simultaneous processing of several genomic regions/individuals, increasing the availability and accuracy of whole-genome data. However, these new approaches may present some ...
High Content Screening of a Kinase-Focused Library Reveals Compounds Broadly-Active against Dengue Viruses
(2013-02-01)
Dengue virus is a mosquito-borne flavivirus that has a large impact in global health. It is considered as one of the medically important arboviruses, and developing a preventive or therapeutic solution remains a top priority ...
Identification and Characterization of Microsatellite Markers Derived from the Whole Genome Analysis of Taenia solium
(Public Library of Science, 2015)
BACKGROUND: Infections with Taenia solium are the most common cause of adult acquired seizures worldwide, and are the leading cause of epilepsy in developing countries. A better understanding of the genetic diversity of ...
De novo assembly and functional annotation of Myrciaria dubia fruit transcriptome reveals multiple metabolic pathways for L-ascorbic acid biosynthesis
(BMC, 2015)
Background. Myrciaria dubia is an Amazonian fruit shrub that produces numerous bioactive phytochemicals, but is best known by its high L-ascorbic acid (AsA) content in fruits. Pronounced variation in AsA content has been ...