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Phylogeography of the freshwater red alga Setacea puiggariana (Rhodophyta, Batrachospermales) in Brazil
(Int Phycological Soc, 2017-01-01)
Phylogeography of Setacea puiggariana, which is widely distributed in southern and south-eastern Brazil, with few records in South America and Africa, was investigated based on mitochondrial genetic markers: the cox2-3 ...
Distribution of QPY and RAH haplotypes of granzyme B gene in distinct Brazilian populations
(SOC BRASILEIRA MEDICINA TROPICALBRASILIA, 2012)
Introduction: The cytolysis mediated by granules is one of the most important effector functions of cytotoxic T lymphocytes and natural killer cells. Recently, three single nucleotide polymorphisms (SNPs) were identified ...
HLA haplotypes in families with type 1 diabetes Haplotipos HLA en familias chilenas con diabetes tipo 1
(1998)
Background: Inherited susceptibility to type 1 diabetes is partially determined by HLA genes. HLA-DQA1 and DQB1 alleles have been chosen as the most sensitive susceptibility markers. Family studies are a good method to ...
HLA-G variability and haplotypes detected by massively parallel sequencing procedures in the geographicaly distinct population samples of Brazil and Cyprus
(2017-03-01)
The HLA-G molecule presents immunomodulatory properties that might inhibit immune responses when interacting with specific Natural Killer and T cell receptors, such as KIR2DL4, ILT2 and ILT4. Thus, HLA-G might influence ...
Evaluation of computational methods for the reconstruction of HLA haplotypes
(WILEY-BLACKWELL, 2010)
Human leukocyte antigen (HLA) haplotypes are frequently evaluated for population history inferences and association studies. However, the available typing techniques for the main HLA loci usually do not allow the determination ...
Functionality of the Interleukin 8 haplotypes in lymphocytes and macrophages in response to gram-negative periodontopathogens
(2019-03-20)
Individuals carrying the ATC/TTC haplotype (Hap-1) in the interleukin 8 (IL8) gene were reported as more susceptible to chronic periodontitis (CP), an infectious disease associated with Gram-negative bacteria, in comparison ...
Atypical β-S haplotypes: classification and genetic modulation in patients with sickle cell anemia
(2019-03-01)
β-S globin haplotype (β S haplotype) characterization in sickle cell anemia (SCA) patients is important because it assists individualized treatment. However, the patient with atypical haplotypes do not present detailed ...
Functionality and opposite roles of two interleukin 4 haplotypes in immune cells
(2017-01-01)
Cytokines expression can be influenced by polymorphisms in their respective coding genes. We associated the CTI/TTD haplotype (Hap-1) and TCI/CCI haplotype (Hap-2) in the IL4 gene formed by the -590, +33 and variable number ...
Functional VEGF haplotypes affect the susceptibility to hypertension
(Nature Publishing GroupLondonInglaterra, 2013)