Aim. This study sought to investigate the in vitro expression profile of high mobility group box 1 (HMGB1) in murine periodontal ligament fibroblasts (mPDL) stimulated with LPS or IL-1 beta and in vivo during ligature-or ...

Background: The high mobility group box 1 (HMGB1) is the prototype of alarmin protein released by stressed or dying cells. The redox state of this protein confers different functions in the regulation of inflammation and ...

As úlceras abomasais atingem bovinos de todas as idades e raças em todos os sistemas de produção, gerando perdas econômicas. A úlcera resulta da isquemia, atraindo leucócitos e macrófagos, estimulando fibroblastos, células ...

HMGB1 protein may act by promoting an inflammatory response. Thus, the goals of this study were to quantify plasma and peritoneal fluid concentrations of HMGB1 in calves with or without congenital umbilical hernia before ...

We have shown that mice infected with mouse hepatitis virus A59 develop autoantibodies (autoAb) to liver and kidney fumarylacetoacetate hydrolase (FAH). Because it has been proposed that the immune system is stimulated by ...

There is a need for new adjuvants that will induce immune responses to subunit vaccines. We show that a short peptide, named Hp91, whose sequence corresponds to an area within the endogenous molecule high mobility group ...