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Differential functional properties between homeoric and heteromeric 5-HT3 receptors
(Sociedad Argentina de Biofísica, 2021)
The serotonin type 3 receptor (5-HT3) is a ligand-gated ion channel that converts the binding of serotonin (5-HT) into a transient cation current and mediates fast excitatory responses in peripheral and central nervous ...
Dendritic assembly of heteromeric gamma-aminobutyric acid type b receptor subunits in hippocampal neurons
(AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY, 2009)
Dendritic assembly of heteromeric gamma-aminobutyric acid type b receptor subunits in hippocampal neurons
(AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY, 2009)
Heteromerization Between the Bradykinin B 2 Receptor and the Angiotensin-(1-7) Mas Receptor Novelty and Significance
(Lippincott Williams, 2016-10)
Bradykinin B2 receptor (B2R) and angiotensin-(1–7) Mas receptor (MasR)–mediated effects are physiologically interconnected. The molecular basis for such cross talk is unknown. It is hypothesized that the cross talk occurs ...
TRPV4, TRPC1, and TRPP2 assemble to form a flow-sensitive heteromeric channel
(Federation of American Societies for Experimental Biology, 2014-11)
Transient receptor potential (TRP) channels, a superfamily of ion channels, can be divided into 7 subfamilies, including TRPV, TRPC, TRPP, and 4 others. Functional TRP channels are tetrameric complexes consisting of 4 ...
Heteromeric TRPV4/TRPC1 channels mediate calcium-sensing receptor-induced relaxations and nitric oxide production in mesenteric arteries: comparative study using wild-type and TRPC1−/- mice
(Landes Bioscience, 2019-01)
We have previously provided pharmacological evidence that stimulation of calcium-sensing receptors (CaSR) induces endothelium-dependent relaxations of rabbit mesenteric arteries through activation of heteromeric TRPV4/TRPC1 ...
Heteromeric TRPV4/TRPC1 channels mediate calcium-sensing receptor-induced relaxations and nitric oxide production in mesenteric arteries: comparative study using wild-type and TRPC1-/- mice
(Taylor & Francis, 2019)
Abstract: We have previously provided pharmacological evidence that stimulation of calcium-sensing receptors (CaSR) induces endothelium-dependent relaxations of rabbit mesenteric arteries through activation of heteromeric ...
5-HT3 Receptor Brain-Type B-Subunits are Differentially Expressed in Heterologous Systems
(American Chemical Society, 2015-05)
Genes for five different 5-HT 3 receptor subunits have been identified. Most of the subunits have multiple isoforms, but two isoforms of the B subunits, brain-type 1 (Br1) and brain-type 2 (Br2) are of particular interest ...
Formation of heteromeric channels by cx26s17f syndromic deafness mutant and cx30 and its consequences on cochlear pathology
(2020)
ABSTRACT Deafness is the most common condition associated with mutations in connexin (Cxs) genes, being mutations in Cx26 gene (GJB2) the most prevalent. Specific mutations in Cx26 also produce syndromic deafness, like ...
PIP1 aquaporins: Intrinsic water channels or PIP2 aquaporin modulators?
(Elsevier Science, 2015)