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Ultrastructural and Molecular Analysis of Ribose-Induced Glycated Reconstructed Human Skin
(Mdpi, 2018-11-01)
Aging depicts one of the major challenges in pharmacology owing to its complexity and heterogeneity. Thereby, advanced glycated end-products modify extracellular matrix proteins, but the consequences on the skin barrier ...
Receptor for advanced glycation end-products axis and coronavirus disease 2019 in inflammatory bowel diseases: A dangerous liaison?
(Baishideng Publishing Group, 2021)
Compelling evidence supports the crucial role of the receptor for advanced
glycation end-products (RAGE) axis activation in many clinical entities. Since the
beginning of the coronavirus disease 2019 pandemic, there is ...
Modulation of the biophysical and biochemical properties of collagen by glycation for tissue engineering applications
(2022)
The structural and functional properties of collagen are modulated by the presence of intramolecular and intermolecular crosslinks. Advanced Glycation End-products (AGEs) can produce intermolecular crosslinks by bonding ...
Effects of the age/rage axis in the platelet activation
(Elsevier B.V., 2020-11-05)
Platelet activity is essential in cardiovascular diseases. Therefore our objective was to evaluate the main effects of activating RAGE in platelets which are still unknown. A search for RAGE expression in different databases ...
Inhibition of RAGE axis signaling: A pharmacological challenge
(Bentham Science Publishers B.V., 2019)
The Receptor for Advanced Glycation End Products (RAGE) is an important cell surface receptor, which belongs to the IgG super family and is now considered as a pattern recognition receptor. Because of its relevance in many ...