Now showing items 1-10 of 1232
Glucocorticoid resistance in chronic diseases
(Elsevier Science, 2016-11)
Glucocorticoids are involved in several responses triggered by a variety of environmental and physiological stimuli. These hormones have a wide-range of regulatory effects in organisms. Synthetic glucocorticoids are ...
Effects of methotrexate on the expression of the translational isoforms of glucocorticoid receptors α and β: Correlation with methotrexate efficacy in rheumatoid arthritis patients
Objectives: To test the effect of MTX on the expression of glucocorticoid receptor (GR) α and β isoforms AB, C and D in peripheral blood mononuclear cells (PBMCs) in culture, from newly diagnosed RA patients and to evaluate ...
LPS regulates the expression of glucocorticoid receptor alpha and beta isoforms and induces a selective glucocorticoid resistance in vitro
(Biomed Central Ltd., 2017)
Background: This study was aimed to evaluate the effect of LPS in glucocorticoid receptor (GR) isoforms expression on different cell lines and PBMC from healthy donors in vitro and glucocorticoid sensitivity of PBMC in ...
Seasonal Changes and Regulation of the Glucocorticoid Receptor in the Testis of the Toad Rhinella arenarum
Several studies indicate that wild free‐living vertebrates seasonally regulate plasma glucocorticoids. However, not only glucocorticoids but also the amount of receptors is important in determining biological responses. ...
Mecanismos moleculares involucrados en la modulación de la actividad del receptor de glucocorticoidesMolecular mechanism underlying glucocorticoid receptor´s activity modulation
(Facultad de Ciencias Exactas y Naturales. Universidad de Buenos Aires, 2010)
NF-kappa b expression predicts clinical outcome for nasal polyposis
(INT RHINOLOGIC SOC, 2010)
Objective: To correlate clinical prognosis of patients with nasal polyps to the expression of p65, c-Fos, GR alpha and GR beta. Methods: A biopsy was obtained at the first evaluation of patients with nasal polyps, and at ...
Enfermedad de Addison. Caso ClínicoAddison's disease. A clinical case.
(SABER ULA, 2005)