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Differential uPA expression by TGF-β1 in gingival fibroblasts
(2006)
Transforming Growth Factor-β1 (TGF-β1) plays a key role in connective tissue remodeling and inflammation. Under pathological conditions, like periodontal disease, fibroblasts may display an altered response to this growth ...
Induction of the myofibroblastic phenotype in human gingival fibroblasts by transforming growth factor-β1: Role of RhoA-ROCK and c-Jun N-terminal kinase signaling pathways
(2006)
Background and Objectives: Myofibroblastic differentiation is an important event in gingival wound healing and chronic inflammation. Transforming frowth factor-β 1 (TGF-β1) is a potent growth factor that has been implicated ...
Induction of the myofibroblastic phenotype in human gingival fibroblasts by transforming growth factor-b1: role of RhoA-ROCK and c-Jun N-terminal kinase signaling pathways
(Blackwell Munksgaard Ltd, 2006-06-05)
Myofibroblastic differentiation is an important event
in gingival wound healing and chronic inflammation. Transforming frowth factorb
1 (TGF-b1) is a potent growth factor that has been implicated in this process.
Gingival ...
Differential uPA expression by TGF-beta 1 in gingival fibroblasts
(INT AMER ASSOC DENTAL RESEARCHI A D R/A A D R, 2006-02)
Transforming Growth Factor-beta 1 (TGF-beta 1) plays a key role in connective tissue remodeling and inflammation. Under pathological conditions, like periodontal disease, fibroblasts may display an altered response to this ...
Epidermal growth factor stimulates urokinase-type plasminogen activator expression in human gingival fibroblasts. Possible modulation by genistein and curcumin
(Blackwell Munksgaard Ltd, 2004-04-08)
Regulation of the extracellular matrix turnover is a crucial process
in wound healing and the progress of periodontal disease. It has been proposed
that urokinase-type plasminogen activator (uPA), under the control of ...
Effect of platelet-rich plasma on cell adhesion, cell migration, and myofibroblastic differentiation in human gingival fibroblasts
(AMER ACAD PERIODONTOLOGY, 2008-04)
Background: Platelet-rich plasma is a blood-derived fraction that contains a high concentration of platelets and growth factors. It was proposed that the use of this platelet concentrate stimulates tissue repair. However, ...
Uncoupled inflammatory, proliferative, and cytoskeletal responses in senescent human gingival fibroblasts
(Wiley, 2020)
Background and objective: Aging is characterized by a decline in tissue structure and function that may be explained by the development of cellular senescence. However, the acquisition of specific phenotypic responses in ...
Methylglyoxal and methylglyoxal-modified collagen as inducers of cellular injury in gingival connective tissue cells
(Wiley, 2016)
Background and Objectives: Methylglyoxal is a toxic product derived from glucose metabolism that plays a role in inflammation, diabetes and aging. In addition, the periodontal pathogen Tannerella forsythensis may also ...
Defective Wound-healing in Aging Gingival Tissue
(Sage, 2014)
Aging may negatively affect gingival wound-healing.
However, little is known about the mechanisms
underlying this phenomenon. The present study
examined the cellular responses associated with gingival
wound-healing in ...
Apoptosis de fibroblastos gingivales en periodontitis.
(2013-07-10)
Introducción: Los fibroblastos gingivales humanos (FGH) tienen un papel importante en la enfermedad periodontal, pues alteran su normal funcionamiento en respuesta a estímulos pro-inflamatorios. Se cree que los fibroblastos ...