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Genotoxic effects of commercial formulations of Chlorpyrifos and Tebuconazole on green algae
(Springer, 2014-09)
The alkaline single-cell gel electrophoresis assay (comet assay) was used for the study of the genotoxic effects of insecticide Chlorpyrifos and fungicide Tebuconazole (commercial formulations) on two freshwater green algae ...
Genotoxicity of aflatoxins and their precursors in human cells
(Elsevier Ireland, 2018-05)
Aflatoxins are found as food contaminant and some of them demonstrate a carcinogenic effect. The aflatoxins biosynthetic pathway involves 15 successive steps. The aim of this study was to compare the toxicity of aflatoxins ...
Oxidative stress and genotoxicity in Rhinella arenarum (Anura: Bufonidae) tadpoles after acute exposure to Ni-Al nanoceramics
(Elsevier Science, 2020-11)
The employ of nanomaterials (NMs) has exponentially grown due to the large number of technological advances in industrial, pharmaceutical and medical areas. That is the case of alumina (Al) nanoparticles which are extensively ...
Trapping of DNA radicals with the nitrone spin trap 5,5-dimethyl-1-pyrroline N-oxide and genotoxic damage: Recent advances using the immuno-spin trapping technology
(Elsevier Science Inc, 2019-10)
Immuno-spin trapping detection of DNA radicals with the nitrone spin trap 5,5-dimethyl-1-pyrrloine N-oxide (DMPO) has made important contributions towards the understanding of DNA radicalization and genotoxicity at sites ...
Toxicity and genotoxicity assessment in sediments from the Matanza-Riachuelo river basin (Argentina) under the influence of heavy metals and organic contaminants
(Academic Press Inc Elsevier Science, 2017-01)
The aim of this study was to investigate the parameters of chemical extraction associated with the detection of toxicity and genotoxicity in sediment sample extracts. Quantitative analysis of metals and polycyclic aromatic ...
Prediction of non-genotoxic carcinogenicity based on genetic profiles of short term exposure assays
(Korean Society of Toxicology, 2016-06)
Non-genotoxic carcinogens are substances that induce tumorigenesis by non-mutagenic mechanisms and long term rodent bioassays are required to identify them. Recent studies have shown that transcription profiling can be ...
Evaluation in situ of genotoxic and cytotoxic response in the diploid/polyploid complex Odontophrynus (Anura: Odontophrynidae) inhabiting agroecosystems
(Pergamon-Elsevier Science Ltd, 2019-02)
Polyploidization has been documented across a wide range of vertebrates. Gene duplication could promote better adaptation to environmental changes and to chronic injury or stress. We investigated if genotoxic and cytotoxic ...
Micronucleus test in fish from a pampasic pond (Argentina): an estimation of the presence of genotoxic compounds
(Begell House, 2001-11)
The Los Padres pond is one of the commonly shallow, polymictic lakes from the so-called depressed Pampa (Argentina). Its watershed includes one affluent, named Los Padres creek, which flows through horticultural lands ...
Dose-independent genotoxic response in A549 cell line exposed to fungicide Iprodione
(Springer, 2020-11)
The fungicide Iprodione is widely applied in vegetables and raises concern for human health. The A549 human lung carcinoma cell line is a suitable model for assessing the toxicological effects of drugs. The goal of this ...
Evaluation of the genotoxicity of aqueous extracts of leaves and stems of Dolichandra unguis-cati (L.) L.G. Lohmann (Bignoniaceae) using the Allium cepa test
(Med Crave editor, 2019-07-29)
The province of Misiones is characterized by its great plant diversity and the use of medicinal plants is common, 80% of its boundaries are international, it borders the Republic of Paraguay to the west and the Republic ...