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GenomicLand: Software for genome-wide association studies and genomic prediction
(Acta Scientiarum. Agronomy, 2019)
Genome-wide association study for feedlot average daily gain in Nellore cattle (Bos indicus)
(Wiley-Blackwell, 2014-06-01)
The genome-wide association study (GWAS) results are presented for average daily gain (ADG) in Nellore cattle. Phenotype of 720 male Bos indicus animals with information of ADG in feedlots and 354147 single-nucleotide ...
Genome-wide analysis of multi- and extensively drug-resistant Mycobacterium tuberculosis
(Springer Nature, 2018)
To characterize the genetic determinants of resistance to antituberculosis drugs, we performed a genome-wide association study (GWAS) of 6,465 Mycobacterium tuberculosis clinical isolates from more than 30 countries. A ...
Genomic signatures of pre-resistance in Mycobacterium tuberculosis.
(Springer Nature, 2021)
Recent advances in bacterial whole-genome sequencing have resulted in a comprehensive catalog of antibiotic resistance genomic signatures in Mycobacterium tuberculosis. With a view to pre-empt the emergence of resistance, ...
Genome-wide association studies and CRISPR/Cas9-mediated gene editing identify regulatory variants influencing eyebrow thickness in humans
(Public Library of Science, 2018)
Hair plays an important role in primates and is clearly subject to adaptive selection. While humans have lost most facial hair, eyebrows are a notable exception. Eyebrow thickness is heritable and widely believed to be ...
Meta-analysis of genome-wide association from genomic prediction models
(Wiley, 2015-11)
Genome-wide association (GWA) studies based on GBLUP models are a common practice in animal breeding. However, effect sizes of GWA tests are small, requiring larger sample sizes to enhance power of detection of rare variants. ...
Gene prioritization based on biological plausibility over genome wide association studies renders new loci associated with type 2 diabetes
(Lippincott Williams, 2009-05)
Purpose: We present an approach to prioritize single nucleotide polymorphisms for further follow-up in genome-wide association studies of type 2 diabetes. Method: The proposed method combines both the use of open data ...