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Norovirus vaccines under development
(Elsevier Ltd, 2018)
© 2017 Elsevier Ltd Noroviruses (NoVs) are one of the leading causes of acute gastroenteritis, including both outbreaks and endemic infections. The development of preventive strategies, including vaccines, for the most ...
Gene-deleted live-attenuated Trypanosoma cruzi parasites as vaccines to protect against Chagas disease
(Expert Reviews, 2014)
Chagas disease is a neglected tropical disease caused by the protozoan parasite Trypanosoma
cruzi. This illness is now becoming global, mainly due to congenital transmission, and so far,
there are no prophylactic or ...
Gene-deleted live-attenuated Trypanosoma cruzi parasites as vaccines to protect against Chagas disease
(Expert Reviews Ltd., 2015)
© Informa UK, Ltd. Chagas disease is a neglected tropical disease caused by the protozoan parasite Trypanosoma cruzi. This illness is now becoming global, mainly due to congenital transmission, and so far, there are no ...
A short hairpin RNA-based adjuvant targeting NF-κB repressor IκBα promotes migration of dermal dendritic cells to draining lymph nodes and antitumor CTL responses induced by DNA vaccination
(Elsevier Ltd, 2017)
© 2017 Elsevier Ltd DNA vaccination is an attractive approach to elicit tumor-specific cytotoxic CD8+ T lymphocytes (CTL), which can mediate protective immunity against tumors. To initiate CTL responses, antigen-encoding ...
Genetic diversity of Bovine Viral Diarrhea Virus from cattle in Chile between 2003 and 2007
(BioMed Central, 2018)
Background: Bovine Viral Diarrhea Virus causes significant economic losses in cattle. BVDV has high genomic
diversity, with two species, BVDV-1 and BVDV-2, and at least twenty-one subgenotypes for BVDV-1 and four
subgenotypes ...
Resistance against infectious pancreatic necrosis exhibits significant genetic variation and is not genetically correlated with harvest weight in rainbow trout (Oncorhynchus mykiss)
(Elsevier, 2017)
Infectious pancreatic necrosis (IPN) is one of the most prevalent and economically important diseases in rainbow trout aquaculture (Oncorhynchus mykiss). Vaccines as a conventional control measure have shown variable results ...
Antigenic characterization of novel H1 influenza A viruses in swine
(Nature, 2020)
Novel H1N2 influenza A viruses (IAVs) in swine have been identified in Chile co-circulating with pandemic H1N1 2009-like (A(H1N1)pdm09-like) viruses. The objective of this study was to characterize antigenically the swine ...
Structural analysis of owl monkey MHC-DR shows that fully-protective malaria vaccine components can be readily used in humans
(2017)
More than 50 years ago the owl monkey (genusAotus) was found to be highly susceptible to developinghuman malaria, making it an excellent experimental model for this disease. Microbes and parasites'(especially malaria) ...
Clinical and Genotypic Spectrum of Chronic Granulomatous Disease in 71 Latin American Patients: First Report From the LASID Registry
(Wiley-Blackwell, 2015)
Aim. We analyzed data from 71 patients with chronic granulomatous disease (CGD) with a confirmed genetic diagnosis, registered in the online Latin American Society of Primary Immunodeficiencies (LASID) database. Results. ...
Association of complement C3d receptor 2 genotypes with the acquisition of HIV infection in a trial of recombinant glycoprotein 120 vaccine
(2020)
Objectives:Complement C3d receptor 2 (CR2) is the main receptor for complement protein C3d and plays an important role in adaptive immune responses. CR2 genetic variants are associated with susceptibility to systemic lupus ...