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Transforming vaccine development
The urgency to develop vaccines against Covid-19 is putting pressure on the long and expensive development
timelines that are normally required for development of lifesaving vaccines. There is a unique opportunity to ...
Reverse genetic systems: Rational design of coronavirus live attenuated vaccines with immune sequelae
Since the end of 2019, the global COVID-19 outbreak has once again made coronaviruses
a hot topic. Vaccines are hoped to be an effective way to stop the spread of the virus.
However, there are no clinically approved ...
Genetics and vaccines in the era of personalized medicine
Vaccines represent the most successful and sustainable tactic to prevent and counteract infection. A vaccine generally improves immunity to a particular disease upon administration by inducing specific protective and ...
Plasmodium vivax vaccine: What is the best way to go?
(Frontiers Media, 2023)
Humoral immune response after genetic immunization is consistently improved by electroporation
(Elsevier B.V., 2008-07-23)
Aiming to evaluate some parameters to influence the immune response to DNA vaccination, we compare three protocols of DNA immunization (i.m. injections, i.m. injections followed by electroporation, and the effect of i.p. ...
Status epilepticus and lymphocytic pneumonitis following hepatitis B vaccination
(ELSEVIER SCIENCE BV, 2008)
The case reported refers to a patient who developed status epilepticus in the day of her third dose of hepatitis B vaccination and we review the literature on this subject. A 12 year-old girl, without a relevant previous ...
Vaccinations and febrile seizures
(Wiley-blackwellMaldenEUA, 2011)
Genetic basis for yellow fever vaccine-associated viscerotropic disease (YEL-AVD): a preliminary report
(Fiocruz/Instituto de Tecnologia em Imunobiológicos, 2019)
Genetic diversity of VAR2CSA ID1-DBL2Xb in worldwide Plasmodium falciparum populations: impact on vaccine design for placental malaria
(Elsevier, 2014)
In placental malaria (PM), sequestration of infected erythrocytes in the placenta is mediated by an interaction between VAR2CSA, a Plasmodium falciparum protein expressed on erythrocytes, and chondroitin sulfate A (CSA) ...