Now showing items 1-10 of 342
Flumecinol, a novel inducer of testosterone 16a-hydroxylation in Male rats
(Informa Healthcare, 1990)
1. Flumecinol, a new inducer of the cytochrome P-450 monooxygenases, was studied in rats as a possible effector of liver microsomal testosterone oxidases. The drug enhanced the total content of liver cytochrome P-450 in ...
Alcohol ingestion, liver glutathione and lipoperoxidation: Metabolic interrelations and pathological implications
Data reviewed here indicate that acute and chronic ethanol ingestion induce a decrease in the concentration of GSH and an increase in lipoperoxidation in the liver both in experimental animals and in man, changes that are ...
Enhancement of rat liver catalase activity dietary cholesterol
The effects of a fat-supplemented diet and clofibrate (ethylchlorophenoxyisobutirate) upon serum lipids and liver catalase activity were studied in male rats. A butter-supplemented diet produced a striking increase of serum ...
The general Assembly of the International Association of Environmental Mutagenesis and Genomics Societies (IAEMGS) in 2017
(BioMed Central, 2018)
Abstract The International Association of Environmental Mutagenesis and Genomics Societies (IAEMGS) is a global organization that promotes applied and basic research on environmental mutagenesis and genomics. ...
Mechanisms Of In-stent Restenosis: A Toxicogenomic In Vitro Study Using Coronary Artery Endothelial And Smooth Muscle Cells
Biological similarities and differences between rats genetically different in alcohol preference
This paper is an inventory of some behavioural, biochemical and pharmacological similarities and differences between two inbred strains of Wistar rats differing in voluntary consumption of ethanol, namely: UChA and UChB ...
Preclinical studies on the pharmacokinetics, safety, and toxicology of oxfendazole: toward first in human studies
(SAGE Publications, 2015)
A 2-week study in rats identified target organs of oxfendazole toxicity to be bone marrow, epididymis, liver, spleen, testis, and thymus. Female rats had greater oxfendazole exposure and exhibited toxicities at lower doses ...
Evaluation of the action of a new metallic-insecticide in genetic material of Allium cepa
(Elsevier B.V., 2014-09-10)
Action of a polyamine putrescine in genetic material of Allium cepa
(Elsevier B.V., 2015-10-16)