The biogenesis of the plant mitochondrial respiratory chain needs the coordinated synthesis and assembly of the products of more than 100 genes located in the nucleus and within the organelle. One of the factors that ...

There are increasing evidences that horizontal gene transfer (HGT) is a critical mechanism of bacterial evolution, while its complete impact remains unclear. A main constraint of HGT effects on microbial evolution seems ...

In the postgenome era many efforts have been dedicated to systematically elucidate the complex web of interacting genes and proteins. These efforts include experimental and computational methods. Microarray technology ...

We evaluated the safety, efficacy and anti-tumour effects of a surgery adjuvant treatment on an equine patient with metastatic malignant melanoma. This approach combined suicide gene therapy with a subcutaneous vaccine ...

Gene filtering is a useful preprocessing technique often applied to microarray datasets. However, it is no common practice because clear guidelines are lacking and it bears the risk of excluding some potentially relevant ...