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Análise da distribuição da frequência de polimorfismos em genes relógio, nos grupos étnicos asiático e caucasiano que compõem a população brasileira
(Universidade Federal de São Paulo (UNIFESP), 2010-04-28)
The Period 3 and Clock genes are important components of the mammalian molecular circadian system. Studies have shown association between polymorphisms in these clock genes and circadian phenotypes in different populations. ...
Suprachiasmatic Nucleus and Subordinate Brain Oscillators: Clock Gene Desynchronization by Neuroinflammation
(2018-03-01)
Objective: The clock genes Period (per) 1 and 2 are essential components in the generation and adjustment of biological circadian rhythms by the suprachiasmatic nucleus (SCN). Both genes are also rhythmically present in ...
Per3 expression in different tissues of Cebus apella
(2016-10-01)
We present a study of Per3 expression in six different tissues of the non-human primate Cebus apella (capuchin monkey). The aim of this study was to verify whether the expression of the Per3 gene in different tissues of ...
Estudo de associações entre o gene PER3 e a sincronização de ritmos circadianos pelo claro/escuro
(Universidade Federal de São Paulo (UNIFESP), 2011-09-28)
Per3 gene is a component of the circadian molecular mechanism. Its function is not completely understood. One of the hypotheses is that Per3 gene may be involved in light synchronization mechanism. The aim of this project ...
A novel association of two non-synonymous polymorphisms in PER2 and PER3 genes with specific diurnal preference subscales
(2013-10)
The circadian system is responsible for the generation and maintenance of physiological and behavioral
rhythms in mammals and allows synchronization with the environment. Different polymorphisms
in clock genes have been ...
The expression of melanopsin and clock genes in Xenopus laevis melanophores and their modulation by melatonin
(Associação Brasileira de Divulgação Científica, 2012)
Vertebrates have a central clock and also several peripheral clocks. Light responses might result from the integration of light signals by these clocks. The dermal melanophores of Xenopus laevis have a photoreceptor molecule ...
Do Caucasian and Asian clocks tick differently?
(Associação Brasileira de Divulgação Científica, 2010-01-01)
The Period 3 and Clock genes are important components of the mammalian molecular circadian system. Studies have shown association between polymorphisms in these clock genes and circadian phenotypes in different populations. ...