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Polymorphisms in Genes Coding for HSP-70 Are Associated with Gastric Cancer and Duodenal Ulcer in a Population at High Risk of Gastric Cancer in Costa Rica
(2013)
Background and Aims. Costa Rica has among the highest incidence and mortality rates
for gastric cancer worldwide. The reasons for this are largely unknown. Polymorphisms
of inflammatory response genes including genes ...
X-ray screening seems to reduce gastric cancer mortality by half in a community-controlled trial in Costa Rica
(British Journal of Cancer 97, p. 837 – 843, 2007-10-02)
X-ray screening of gastric cancer is broadly used in Japan, although no controlled trial has proved its effectiveness. This study evaluates the impact of an X-ray screening demonstrative intervention to reduce gastric ...
Urokinase plasminogen activator receptor is expressed in invasive cells in gastric carcinomas from high- and low-risk countries
(International Journal of Cancer 146 año 2009 p. 405–415, 2009-07-16)
Gastric cancer is the second cancer causing death worldwide. Both incidence and mortality rates vary according to
geographical regions. The receptor for urokinase plasminogen activator (uPAR) is involved in extracellular ...
Association of interleukin-1B and interleukin-1RN polymorphisms with gastric cancer in a high-risk population of Costa Rica
(Clinical and Experimental Medicine 5 p.169-176, 2005-09-13)
Several risk factors have been associated with gastric cancer, among them Helicobacter pylori infection. This bacterium yields inflammation, the degree of which depends on the bacterial strain and the severity of the host ...
La inflamacion y su papel en el desarrollo del cáncer gástrico
(Acta Medica Cnstarricense Vol 51 (2):76-82, abril-junio 2009, 2009-04)
La infección por Helicobacter pylori produce, en algunos pacientes, inflamación crónica en el estómago, gastritis atrófica y cáncer gástrico. Los mecanismos moleculares que conducen de la infección a la inflamación crónica ...
Distribution of Open Reading Frames of Plasticity Region of Strain J99 in Helicobacter pylori Strains Isolated from Gastric Carcinoma and Gastritis Patients in Costa Rica
(2000)
The plasticity region of Helicobacter pylori strain J99 is a large chromosomal segment containing 33 strain-specific open reading frames (ORFs) with characteristics of a pathogenicity island. To study the diversity of the ...
Tissue Inhibitor of Metalloproteinase-1 Is Confined to Tumor-Associated Myofibroblasts and Is Increased With Progression in Gastric Adenocarcinoma
(2016)
The tissue inhibitor of metalloproteinase-1 (TIMP-1) inhibits the extracellular matrix–degrading activity of several matrix metalloproteinases, thereby regulating cancer cell invasion and metastasis. Studies describing the ...
Asociación del polimorfismo del codon 72 del gen P53 con el riesgo de cáncer gástrico en una población de alto riesgo de Costa Rica
(Revista de Biología Tropical 53 (3-4): 317-324, 2005, 2005-10-03)
El cáncer gástrico es la segunda causa de muerte por cáncer en el mundo. Varios factores han sido asociados con el riesgo de llegar a desarrollarlo, entre ellos la predisposición genética. El gen p53 presenta un polimorfismo ...
Pepsinógenos séricos para detectar cáncer gástrico en Costa Rica
(Ada Bioquirnice Minion Latinoamericana ; 37 (4): 357-62, 2003)
Las concentraciones de pepsinagenos (PG) I y II en suero, reflejan el estado funcional y morfológico de la mucosa gástrica. En este estudio se determinaron los puntos de corte óptimos de los niveles séricos de PGI, PGII y ...
Helicobater pylori. ¿Es posible la erradicación?
(1999)
Objetivo:
Erradicar H. pylori en pacientes dispepticos
de una población de alto riesgo de cancer
gástrico
Poblacion y metodos:
A 174 pacientes dispepticos, de una
poblacion de alto riesgo de cancer gastric°, se
les ...