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Glycolytic oscillations and intracellular K+ concentration are strongly coupled in the yeast Saccharomyces cerevisiae
(Elsevier Science Inc., 2020-03)
We measured temporal oscillations of intracellular K+ concentration in yeast cells exhibiting glycolytic oscillations using fluorescence spectroscopy and microscopy methods. These oscillations showed the same period as ...
Is a constant low-entropy process at the root of glycolytic oscillations?
(Springer, 2018-09)
We measured temporal oscillations in thermodynamic variables such as temperature, heat flux, and cellular volume in suspensions of non-dividing yeast cells which exhibit temporal glycolytic oscillations. Oscillations in ...
The dynamics of intracellular water constrains glycolytic oscillations in Saccharomyces cerevisiae
(Nature Publishing Group, 2017-12-24)
We explored the dynamic coupling of intracellular water with metabolism in yeast cells. Using the polarity-sensitive probe 6-acetyl-2-dimethylaminonaphthalene (ACDAN), we show that glycolytic oscillations in the yeast S. ...
Effect of macromolecular crowding on the kinetics of glycolytic enzymes and the behaviour of glycolysis in yeast
(Royal Society of Chemistry, 2018-10)
Water is involved in all aspects of biological activity, both as a solvent and as a reactant. It is hypothesized that intracellular water is in a highly structured state due to the high concentrations of macromolecules in ...
Cellular metabolism and colloids: Realistically linking physiology and biological physical chemistry
(Pergamon-Elsevier Science Ltd, 2021-07)
Important concepts from colloidal physical chemistry such as coacervation, phase transitions, emergent properties and ionic association, are currently emerging in the lexicon of cellular biology, prompted mostly by recent ...
Turing patterns inside cells
(Public Library of Science, 2007-12)
Concentration gradients inside cells are involved in key processes such as cell division and morphogenesis. Here we show that a model of the enzymatic step catalized by phosphofructokinase (PFK), a step which is responsible ...
Coupled response of membrane hydration with oscillating metabolism in live cells: An alternative way to modulate structural aspects of biological membranes?
(MDPI AG, 2019-11)
We propose that active metabolic processes may regulate structural changes in biological membranes via the physical state of cell water. This proposition is based on recent results obtained from our group in yeast cells ...
Real-Time Measurement of Glycolytic Fluxes In Brain Cells In Situ
(2010)
Processing of information in the brain is metabolically expensive. The brain represents only 2% of
our body mass, but consumes 20% of its oxygen and glucose. Glucose, transported by the blood, is
the major source of energy ...
Análise global de sistemas diferenciais polinomiaisGlobal analysis of polynomial differential systems
(Universidade Federal de ViçosaMatemática, 2022)
Modelado de la participación del Adenosín Trifosfato (ATP) en la actividad eléctrica de las células alfa (α) del páncreas
(Universidad Autónoma Metropolitana (México). Unidad Azcapotzalco. Coordinación de Servicios de Información., 2018-10)
Esta tesis tiene como objetivo proponer un modelo computacional que permita entender la participación del adenosín trifosfato (ATP) en la autorregulación de la célula alfa del páncreas, enfocándose tanto en su actividad ...