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Major roles of for pyrimidine dimers, nucleotide excision repair and ATR in the alternative splicing response to UV irradiation
(Elsevier B.V., 2017-03-21)
We have previously found that UV irradiation promotes RNA polymerase II (RNAPII) hyperphosphorylation and subsequent changes in alternative splicing (AS). We show now that UV-induced DNA damage is not only necessary but ...
Estudo do gene da fotoliase de tripanossomatídeos: expressão heteróloga do gene de Trypanosoma brucei EM Trypanosoma cruzi
(Universidade Federal de Minas GeraisUFMG, 2014-03-31)
The Trypanosoma cruzi and Trypanosoma brucei are the protozoa parasites that cause African and American trypanosomiasis. Both are characterized by the presence of a single flagellum, a kinetoplast, which is elongated and ...
Contribution of genomic and proteomic studies toward understanding hexavalent chromium stress resistance
(Taylor & Francis, 2017)
The development of efficient biological processes (accompanied by a global analysis of macromolecules) offers numerous opportunities in the treatment of environmental heavy metal pollution. The knowledge about the interaction ...
Gene expression profiling in the injured spinal cord of trachemys scripta elegans: an amniote with self-repair capabilities
(Elsevier, 2017)
Slider turtles are the only known amniotes with self-repair mechanisms of the spinal cord that lead to substantial functional recovery. Their strategic phylogenetic position makes them a relevant model to investigate the ...
The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas disease
(American Association for the Advancement of Science, 2012)
The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas disease
(American Association for the Advancement of Science, 2012)
p53 Mutant Human Glioma Cells Are Sensitive to UV-C-Induced Apoptosis Due to Impaired Cyclobutane Pyrimidine Dimer Removal
(AMER ASSOC CANCER RESEARCH, 2009)
The p53 protein is a key regulator of cell responses to DNA damage, and it has been shown that It sensitizes glioma cells to the alkylating agent temozolomide by up-regulating the extrinsic apoptotic pathway, whereas it ...
Genome wide comparative analysis of the effects of PRMT5 and PRMT4/CARM1 arginine methyltransferases on the Arabidopsis thaliana transcriptome
(BioMed Central, 2015-03)
BACKGROUND: Methylation at arginine residues (R) is an important post-translational modification that regulates a myriad of essential cellular processes in eukaryotes, such as transcriptional regulation, RNA processing, ...
Xylella fastidiosa: An in vivo system to study possible survival strategies within citrus xylem vessels based on global gene expression analysis
(UNIV CATOLICA DE VALPARAISOVALPARAISO, 2012)
Xylella fastidiosa inhabits the plant xylem, a nutrient-poor environment, so that mechanisms to sense and respond to adverse environmental conditions are extremely important for bacterial survival in the plant host. Although ...
Xylella fastidiosa: An in vivo system to study possible survival strategies within citrus xylem vessels based on global gene expression analysis
(Universidade Católica de Valparaíso, 2012-05-15)
Xylella fastidiosa inhabits the plant xylem, a nutrient-poor environment, so that mechanisms to sense and respond to adverse environmental conditions are extremely important for bacterial survival in the plant host. Although ...