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An evaluation of the genotoxic and cytotoxic effects of the anti-obesity drugs sibutramine and fenproporex
(SAGE PUBLICATIONS LTD, 2010)
Anti-obesity medications deserve special considerations at the present time due to an increasing number of overweight and obese people who require these therapeutic alternatives. Obesity is positively associated with several ...
Evaluation of the genotoxic potential due to the action of an effluent contaminated with chromium, by the comet assay in CHO-K1 cultures
(2005-12-01)
The comet assay technique has been considered to be more efficient in the biomonitoring of aquatic environments that the micronucleus and sister chromatid exchange techniques. The comet assay has been used to determine ...
Evaluation of the genotoxic potential due to the action of an effluent contaminated with chromium, by the comet assay in CHO-K1 cultures
(2005-12-01)
The comet assay technique has been considered to be more efficient in the biomonitoring of aquatic environments that the micronucleus and sister chromatid exchange techniques. The comet assay has been used to determine ...
Chemoprevention assessment, genotoxicity and cytotoxicity of flavonoids from Inga laurina leaves (FABACEAE)
(2019-01-01)
This study aimed to identify and evaluate the cytotoxicity, genotoxicity, antigenotoxicity and chemoprevention assessment of flavonoids myricetin-3-O-(2″-O-galloyl)-α-rhamnopyranoside and myricetin-3-rhamnoside from Inga ...
Analysis of Aloe vera cytotoxicity and genotoxicity associated with endodontic medication and laser photobiomodulation
(2018-01-01)
This study aims to evaluate, in vitro, the effect of Aloe vera associated with endodontic medication, with or without laser photobiomodulation (FTL) irradiation in FP6 human pulp fibroblasts. The materials were divided ...
Mutagenic and genotoxic effect of hydroxyurea
(International Journal Of Biomedical Science : Ijbs, 2011)
The hydroxyurea, a cytotoxic drug, is the mainly available therapeutical strategy for the treatment of sickle cell disease. This study aimed to evaluate the mutagenic and genotoxic potential of the hydroxyurea through the ...
Genotoxic effect of phenol on the cells of onion (Allium cepa ) roots
(2013)
The roots of onion (Allium cepa ) stand out for having cells with large size and small number of chromosomes. These characteristics make them useful in bioassays for the measurement of a variety of cytogenetic and morphological ...
In Vitro Genotoxic Effects of Four Helichrysum Species in Human Lymphocytes Cultures
(Sociedad de Biología de Chile, 2010)
Putative mechanisms of genotoxicity induced by fluoride: a comprehensive review
(Springer Heidelberg, 2017)
Genotoxicity is the ability of an agent to produce damage on the DNA molecule. Considering the strong evidence for a relationship between genetic damage and carcinogenesis, to elucidate the putative mechanisms of genotoxicity ...