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Chitosan-based nanoparticles for Intracellular delivery of ISAV fusion protein cDNA into melanoma cells: a path to develop oncolytic anticancer therapies
(Hindawi, 2020)
Oncolytic virus therapy has been tested against cancer in preclinical models and clinical assays. Current evidence shows that viruses induce cytopathic effects associated with fusogenic protein-mediated syncytium formation ...
Palmitoylation of the feline immunodeficiency virus envelope glycoprotein and its effect on fusion activity and envelope incorporation into virions
(Universidad de Belgrano - Facultad de Ciencias Exactas y Naturales - Proyectos de Investigación, 2012)
The feline immunodeficiency virus (FIV) envelope glycoprotein (Env) possesses a short cytoplasmic
domain of 53 amino acids containing four highly conserved cysteines at Env positions 804, 811, 815 and
848. Since ...
Liposome fusion mediated by hydrophobic magnetic nanoparticles stabilized with oleic acid and modulated by an external magnetic field
(American Chemical Society, 2021-02)
Membrane fusion is considered relevant in countless scientific areas and biotechnological processes, ranging from vital life events to biomedicine, pharmaceuticals, and materials engineering, among others. In this study, ...
Importance of the short cytoplasmic domain of the feline immunodeficiency virus transmembrane glycoprotein for fusion activity and envelope glycoprotein incorporation into virions
(Universidad de Belgrano - Facultad de Ciencias Exactas y Naturales - Proyectos de Investigación, 2007)
The mature form of the envelope (Env) glycoprotein of lentiviruses is a heterodimer composed of the surface (SU) and transmembrane (TM)
subunits. Feline immunodeficiency virus (FIV) possesses a TM glycoprotein with a ...
Chitosan-based delivery of avian reovirus fusogenic protein p10 gene: in vitro and in vivo studies towards a new vaccine against melanoma
(Hindawi, 2020)
Reovirus is known to have an anticancer effect in both the preclinical and clinical assays. Current evidence suggests that the reovirus-mediated impact on tumor growth depends on the activation of specific antitumor immune ...
Dead tumor cells expressing infectious salmon anemia virus fusogenic protein favor antigen cross-priming in vitro
(Frontiers media SA, 2017)
Antigen cross-presentation is a crucial step in the assembly of an antitumor immune response leading to activation of naive CD8 T cells. This process has been extensively used in clinical trials, in which dendritic cells ...
StarD7 behaves as a fusogenic protein in model and cell membrane bilayers
(Elsevier Science, 2012-03-03)
StarD7 is a surface active protein, structurally related with the START lipid transport family. So, the present work was aimed at elucidating a potential mechanism of action for StarD7 that could be related to its interaction ...
Processing, fusogenicity, virion incorporation and CXCR4-binding activity of a feline immunodeficiency virus envelope glycoprotein lacking the two conserved N-glycosylation sites at the C-terminus of the V3 domain
(Springer Wien, 2016-03)
The process of feline immunodeficiency virus (FIV) entry into its target cells is initiated by the association of the surface (SU) subunit of the viral envelope glycoprotein (Env) with the cellular receptors CD134 and ...
Pressure-induced fusogenic conformation of vesicular stomatitis virus glycoprotein
(Amer Chemical SocWashingtonEUA, 2003)